Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Alzheimer's disease amyloid A4 protein precursor Homo sapiens P05067 P09000 Q16011 B2R5V1 B4DII8 D3DSD1 D3DSD2 D3DSD3 P78438 Q13764 Q13778 Q13793 Q16014 Q16019 Q16020 Q6GSC0 Q8WZ99 Q9BT38 Q9UC33 Q9UCA9 Q9UCB6 Q9UCC8 Q9UCD1 Q9UQ58 1.5 XRAY Kunitz protease inhibitor domain N/A NMR by similarity N/A NMR by similarity N/A NMR according to fig 1 N/A NMR by similarity N/A NMR by similarity 2.5 XRAY by similarity 2.1 XRAY by similarity 1.80 XRAY >>The predominant isoform in neuronal tissues is a 695-residue protein that consists of a large N-terminal extracellular region, a transmembrane region and a small cytoplasmic tail2.<< Nat Struct Biol. 1999 Apr;6(4):327-31. N/A NMR The N-terminal border was determined based on proteolysis of the whole extracellular domain 2.80 XRAY Heparan sulfate proteoglycans, the putative ligand for the precursor present in extracellular matrix, bind to E2 at a conserved and positively charged site near the dimer interface. 1.8 XRAY by similarity N/A NMR The amyloid beta-peptide (Abeta), the major component of these extracellular deposits, N/A NMR The amyloid beta-peptide (Abeta), the major component of these extracellular deposits, 2.60 XRAY by similarity 1.61 XRAY APP can function as a metalloprotein and modulate copper (Cu) transport, presumably via its extracellular Cu-binding domain (CuBD). 1.60 XRAY APP can function as a metalloprotein and modulate copper (Cu) transport, presumably via its extracellular Cu-binding domain (CuBD). 1.65 XRAY APP can function as a metalloprotein and modulate copper (Cu) transport, presumably via its extracellular Cu-binding domain (CuBD). 2.40 XRAY APP can function as a metalloprotein and modulate copper (Cu) transport, presumably via its extracellular Cu-binding domain (CuBD). 2.50 XRAY APP can function as a metalloprotein and modulate copper (Cu) transport, presumably via its extracellular Cu-binding domain (CuBD). 0.85 XRAY APP can function as a metalloprotein and modulate copper (Cu) transport, presumably via its extracellular Cu-binding domain (CuBD). N/A NMR by similarity N/A NMR by similarity N/A NMR by similarity to chain: A (see PDBTM: 2loh) N/A NMR According to 21907289/text N/A NMR According to 21907289/text MLPGLALLLL AAWTARALEV PTDGNAGLLA EPQIAMFCGR LNMHMNVQNG KWDSDPSGTK TCIDTKEGIL QYCQEVYPEL QITNVVEANQ PVTIQNWCKR GRKQCKTHPH FVIPYRCLVG EFVSDALLVP DKCKFLHQER MDVCETHLHW HTVAKETCSE KSTNLHDYGM LLPCGIDKFR GVEFVCCPLA EESDNVDSAD AEEDDSDVWW GGADTDYADG SEDKVVEVAE EEEVAEVEEE EADDDEDDED GDEVEEEAEE PYEEATERTT SIATTTTTTT ESVEEVVREV CSEQAETGPC RAMISRWYFD VTEGKCAPFF YGGCGGNRNN FDTEEYCMAV CGSAMSQSLL KTTQEPLARD PVKLPTTAAS TPDAVDKYLE TPGDENEHAH FQKAKERLEA KHRERMSQVM REWEEAERQA KNLPKADKKA VIQHFQEKVE SLEQEAANER QQLVETHMAR VEAMLNDRRR LALENYITAL QAVPPRPRHV FNMLKKYVRA EQKDRQHTLK HFEHVRMVDP KKAAQIRSQV MTHLRVIYER MNQSLSLLYN VPAVAEEIQD EVDELLQKEQ NYSDDVLANM ISEPRISYGN DALMPSLTET KTTVELLPVN GEFSLDDLQP WHSFGADSVP ANTENEVEPV DARPAADRGL TTRPGSGLTN IKTEEISEVK MDAEFRHDSG YEVHHQKLVF FAEDVGSNKG AIIGLMVGGV VIATVIVITL VMLKKKQYTS IHHGVVEVDA AVTPEERHLS KMQQNGYENP TYKFFEQMQN Plasma membrane;Cytoplasm;Extracellular 89 Protease Signal Peptidase Structure PDBTM PostTransMod NGlyc Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc Structure PDBTM PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM PostTransMod NGlyc Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM PostTransMod NGlyc Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Protease Partial Proteolysis (ProtK protease) Protease Partial Proteolysis (Tryp protease) Biochemistry. 1992 Jun 23;31(24):5621-31. Science. 1991 Jul 12;253(5016):179-82. Biochemistry. 1990 Oct 30;29(43):10018-22. EMBO J 1988 Apr;7(4):949-57 Residue numbers in the article were corrected, according to the alternative splicing. In type695 (used in the article) the 290-364 region is missing, therefore 75 was added to residue number if it was larger than 290. Biochemistry. 1994 Jun 28;33(25):7788-96. J Mol Biol. 1993 Apr 5;230(3):919-33. J Mol Biol. 1993 Apr 5;230(3):934-49. Biochemistry 1998 Aug 4;37(31):11064-77 NMR structure Nat Struct Biol. 1999 Apr;6(4):327-31. J Struct Biol. 2000 Jun;130(2-3):142-52. J Biol Chem. 2003 May 9;278(19):17401-7. Epub 2003 Feb 28. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Mol Cell. 2004 Aug 13;15(3):343-53. J Biol Chem. 2005 Oct 28;280(43):36165-75. Epub 2005 Aug 6. J Biol Chem. 2006 Jan 27;281(4):2151-61. J Proteome Res. 2005 Nov-Dec;4(6):2070-80. 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Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License BCS1 protein Saccharomyces cerevisiae P32839 Q06404 D6VT07 MSDKPIDIQY DKQATPNLSG VITPPTNETG NDSVREKLSK LVGDAMSNNP YFAAGGGLMI LGTGLAVARS GIIKASRVLY RQMIVDLEIQ SKDKSYAWFL TWMAKHPQRV SRHLSVRTNY IQHDNGSVST KFSLVPGPGN HWIRYKGAFI LIKRERSAKM IDIANGSPFE TVTLTTLYRD KHLFDDILNE AKDIALKTTE GKTVIYTSFG PEWRKFGQPK AKRMLPSVIL DSGIKEGILD DVYDFMKNGK WYSDRGIPYR RGYLLYGPPG SGKTSFIQAL AGELDYNICI LNLSENNLTD DRLNHLMNNM PERSILLLED IDAAFNKRSQ TGEQGFHSSV TFSGLLNALD GVTSSEETIT FMTTNHPEKL DAAIMRPGRI DYKVFVGNAT PYQVEKMFMK FYPGETDICK KFVNSVKELD ITVSTAQLQG LFVMNKDAPH DALKMVSSLR NANHIF Mitochondrial inner membrane;Matrix;Inter membrane space 90 Protease Partial Proteolysis (ProtK protease) EMBO J 1996 Feb 1;15(3):479-87 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License T-cell antigen CD7 precursor Homo sapiens P09564 MAGPPRLLLL PLLLALARGL PGALAAQEVQ QSPHCTTVPV GASVNITCST SGGLRGIYLR QLGPQPQDII YYEDGVVPTT DRRFRGRIDF SGSQDNLTIT MHRLQLSDTG TYTCQAITEV NVYGSGTLVL VTEEQSQGWH RCSDAPPRAS ALPAPPTGSA LPDPQTASAL PDPPAASALP AALAVISFLL GLGLGVACVL ARTQIKKLCS WRDKNSAACV VYEDMSHSRC NTLSSPNQYQ Plasma membrane;Cytoplasm;Extracellular 96 Immunolocalisation Immunolocalisation PostTransMod NGlyc PostTransMod NGlyc Immunolocalisation J Immunol 1989 Dec 1;143(11):3632-40 J Proteome Res. 2009 Feb;8(2):651-61. doi: 10.1021/pr8008012. Nat Biotechnol. 2009 Apr;27(4):378-86. doi: 10.1038/nbt.1532. Epub 2009 Apr 6. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Capsid protein G8P Pseudomonas phage Pf3 P03623 MQSVITDVTG QLTAVQADIT TIGGAIIVLA AVVLGIRWIK AQFF Bacterial inner membrane;Cytoplasm;Periplasmic space 77 Protease Partial Proteolysis (ProtK protease) J Mol Biol 1998;283(1):155-77 XRAY structure EMBO J 1999 Nov 15;18(22):6299-306 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome P450 52A1 Candida tropicalis P10615 MSSSPSIAQE FLATITPYVE YCQENYTKWY YFIPLVILSL NLISMLHTKY LERKFKAKPL AVYVQDYTFC LITPLVLIYY KSKGTVMQFA CDLWDKNLIV SDPKAKTIGL KILGIPLIET KDPENVKAIL ATQFNDFSLG TRHDFLYSLL GDGIFTLDGA GWKHSRTMLR PQFAREQVSH VKLLEPHMQV LFKHIRKHHG QTFDIQELFF RLTVDSATEF LLGESAESLR DESVGLTPTT KDFDGRNEFA DAFNYSQTNQ AYRFLLQQMY WILNGSEFRK SIAIVHKFAD HYVQKALELT DEDLEKKEGY VFLFELAKQT RDPKVLRDQL LNILVAGRDT TAGLLSFLFF ELSRNPEIFA KLREEIENKF GLGQDARVEE ISFETLKSCE YLKAVINETL RIYPSVPHNF RVATRNTTLP RGGGEGGLSP IAIKKGQVVM YTILATHRDK DIYGEDAYVF RPERWFEPET RKLGWAYVPF NGGPRICLGQ QFALTEASYV TVRLLQEFGN LKQDPNTEYP PKLQNTLTLS LFEGAEVQMY LIL Endoplasmic reticulum membrane;Cytoplasm;Cysternal space 63 Fusion HIS Fusion HIS Eur J Biochem 1993 Sep 1;216(2):477-85 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome P450 52A2 Candida tropicalis P30607 MSIQDIVETY STKWYVVVLV ALIVYKVFDF FYARYLMYKL GAKPFLQSQT DGYLGFRVPF ELMGKKSEGT LIDFTYQRTL ELDNPDIPTF TFPIFSVLII STLEPDNIKA ILATQFNDFS LGTRHSHFAP LLGDGIFTLD GAGWKHSRSM LRPQFAREQV SHVKLLEPHM QVFFKHIRKH HGQTFDIQEL FFRLTVDSAT EFLFGESVES LRDESIGMLN DALDFDGKAG FADAFNYSQN YLASRALMQQ MYWILNGKKF KECNAKVHKF ADYYVEKALE LTPDQLEKQD GYVFLYELVK QTRDRQVLRD QLLNILVAGR DTTAGLLSFV FFELARTPRV ANKLREEIED KFGLGQDARV EEISFESLKS CEYLKAVLNE CLRLYPSVPQ NFRVATRNTT LPRGGGKDGL SPVLVRKGQT VMYSVYAAHR NKQIYGEDAL EFRPERWFEP ETKKLGWAFL PFNGGPRICL GQQFALTEAS YVTVRLLQEF SHLTMDPNTE YSPKKMSHLT MSLFDGANIQ MY Endoplasmic reticulum membrane;Cytoplasm;Cysternal space 94 Fusion HIS Fusion HIS Eur J Biochem 1993 Sep 1;216(2):477-85 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Colicin V secretion protein cvaA Escherichia coli P22519 MKWQGRAILL PGIPLWLIML GSIVFITAFL MFIIVGTYSR RVNVSGEVTT WPRAVNIYSG VQGFVVRQFV HEGQLIKKGD PVYLIDISKS TRNGIVTDNH RRDIENQLVR VDNIISRLEE SKKITLDTLE KQRLQYTDAF RRSSDIIQRA EEGIKIMKNN MENYRYYQSK GLINKDQLTN QVALYYQQQN NLLSLSGQNE QNALQITTLE SQIQTQAADF DNRIYQMELQ RLELQKELVN TDVEGEIIIR ALSDGKVDSL SVTVGQMVNT GDSLLQVIPE NIENYYLILW VPNDAVPYIS AGDKVNIRYE AFPSEKFGQF SATVKTISRT PASTQEMLTY KGAPQNTPGA SVPWYKVIAT PEKQIIRYDE KYLPLENGMK AESTLFLEKR RIYQWMLSPF YDMKHSATGP IND Bacterial inner membrane;Cytoplasm;Periplasmic space 89 Fusion PhoA Fusion PhoA Fusion PhoA Fusion PhoA Fusion PhoA Fusion PhoA Fusion PhoA Fusion PhoA Fusion PhoA Fusion PhoA Fusion PhoA J Bacteriol 1995 Nov;177(21):6153-9 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome B5 Homo sapiens P00167 A8MV91 F8WEU4 Q6IB14 AEQSDEAVKY YTLEEIQKHN HSKSTWLILH HKVYDLTKFL EEHPGGEEVL REQAGGDATE NFEDVGHSTD AREMSKTFII GELHPDDRPK LNKPPETLIT TIDSSSSWWT NWVIPAISAV AVALMYRLYM AED Endoplasmic reticulum membrane;Cytoplasm;Cysternal space 97 Protease Partial Proteolysis (GluC protease) Protease Partial Proteolysis (Tryp protease) Protease Partial Proteolysis (GluC protease) Protease Partial Proteolysis (GluC protease) Protease Partial Proteolysis (GluC protease) Protease Partial Proteolysis (ProtK protease) Protease Partial Proteolysis (Tryp protease) Biochim Biophys Acta 1989 Jul 27;997(1-2):121-30 J Biol Chem 1995 Feb 17;270(7):3414-22 J Biochem (Tokyo) 1996 Oct;120(4):828-33 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Apocytochrome F precursor Pisum sativum P00155 MQTRNAFSWI KKEITRSISV LLMIYIITRA PISNAYPIFA QQGYENPREA TGRIVCANCH LANKPVDIEV PQAVLPDTVF EAVVRIPYDM QVKQVLANGK KGALNVGAVL ILPEGFELAP PHRLSPQIKE KIGNLSFQSY RPTKKNILVI GPVPGKKYSE ITFPILSPDP ATKRDVYFLK YPLYVGGNRG RGQIYPDGSK SNNNVSNATA TGVVKQIIRK EKGGYEITIV DASDGSEVID IIPPGPELLV SEGESIKLDQ PLTSNPNVGG FGQGDAEIVL QDPLRVQGLL LFLASIILAQ ILLVLKKKQF EKVQLSEMNF Chloroplast inner membrane;Stroma;Inter membrane space 99 Protease Partial Proteolysis (ProtK protease) Protease Partial Proteolysis (ProtK protease) Cell 1984 Feb;36(2):555-62 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License DnaJ-like protein djlA Escherichia coli P31680 Q6IU30 MQYWGKIIGV AVALLMGGGF WGVVLGLLIG HMFDKARSRK MAWFANQRER QALFFATTFE VMGHLTKSKG RVTEADIHIA SQLMDRMNLH GASRTAAQNA FRVGKSDNYP LREKMRQFRS VCFGRFDLIR MFLEIQIQAA FADGSLHPNE RAVLYVIAEE LGISRAQFDQ FLRMMQGGAQ FGGGYQQQTG GGNWQQAQRG PTLEDACNVL GVKPTDDATT IKRAYRKLMS EHHPDKLVAK GLPPEMMEMA KQKAQEIQQA YELIKQQKGF K Bacterial inner membrane;Cytoplasm;Periplasmic space 83 Protease Partial Proteolysis (Tryp protease) Mol Microbiol 1996 Jun;20(6):1273-86 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License General secretion pathway protein K, OutK Pectobacterium carotovorum subsp. carotovorum P31706 MRSRQRGAAL LVVLLILALM VTIAAVITER TGKAFLRTES HLSRQQAKWY ALGAETLSGQ ILQRDARNMP GRTFAGQNWS QPGLRFPVDG GEITGQISDA RTCFNVNAIN QGVDNESTLV KTPYPAQVFR LLLKNLGEET DRAEKITAAV RDWIDADNYP SANGAEDDVY AALPVPYRTA NQRMSEISEL RSVYGIDSDL YRRLLPYVCA LPVDAMSINI NTLTEFDAPL LSAVFLNEMT MSQAKALVQQ RPRMGWASLE VLQQTGLLPP NSKNTAQRVL AVKSEWFFVK LQVRVGDSDF HQRSLLHLSG QKVQVVQRQY GGYRTVNP Bacterial inner membrane;Cytoplasm;Periplasmic space 89 Fusion BlaM 160 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 160 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 160 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 160 Fusion BlaM 35 Fusion BlaM 35 Mol Microbiol 1994 May;12(3):445-57 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Biopolymer transport exbD protein Escherichia coli P0ABV2 P18784 Q2M9J3 MAMHLNENLD DNGEMHDINV TPFIDVMLVL LIIFMVAAPL ATVDVKVNLP ASTSTPQPRP EKPVYLSVKA DNSMFIGNDP VTDETMITAL NALTEGKKDT TIFFRADKTV DYETLMKVMD TLHQAGYLKI GLVGEETAKA K Bacterial inner membrane;Cytoplasm;Periplasmic space 87 Fusion BlaM Fusion BlaM Structure PDB Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM J Bacteriol 1992 Aug;174(16):5485-7 Mol Microbiol. 2007 Nov;66(4):872-89. Epub 2007 Oct 10. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Formate dehydrogenase-O, iron-sulfur subunit Escherichia coli P32175 P0AAJ6 P0AAJ5 Q2M8J0 P0AAJ7 MAYQSQDIIR RSATNGLTPA PQARDFQEEV AKLIDVTTCI GCKACQVACS EWNDIRDTVG NNIGVYDNPN DLSAKSWTVM RFSEVEQNDK LEWLIRKDGC MHCSDPGCLK ACPAEGAIIQ YANGIVDFQS EQCIGCGYCI AGCPFDIPRL NPEDNRVYKC TLCVDRVVVG QEPACVKTCP TGAIHFGTKE SMKTLASERV AELKTRGYDN AGLYDPAGVG GTHVMYVLHH ADKPNLYHGL PENPEISETV KFWKGIWKPL AAVGFAATFA ASIFHYVGVG PNRADEEENN LHEEKDEERK Bacterial inner membrane;Cytoplasm;Periplasmic space 95 Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM Protease Partial Proteolysis (ProtK protease) Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM Protease Partial Proteolysis (ProtK protease) Fusion BlaM J Bacteriol 1998 Dec;180(24):6625-34 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cell division protein ftsH Escherichia coli P28691 P0AAI3 Q2M934 P0AAI4 1.50 XRAY The crystal structure of the ATPase module of FtsH has been solved MAKNLILWLV IAVVLMSVFQ SFGPSESNGR KVDYSTFLQE VNNDQVREAR INGREINVTK KDSNRYTTYI PVQDPKLLDN LLTKNVKVVG EPPEEPSLLA SIFISWFPML LLIGVWIFFM RQMQGGGGKG AMSFGKSKAR MLTEDQIKTT FADVAGCDEA KEEVAELVEY LREPSRFQKL GGKIPKGVLM VGPPGTGKTL LAKAIAGEAK VPFFTISGSD FVEMFVGVGA SRVRDMFEQA KKAAPCIIFI DEIDAVGRQR GAGLGGGHDE REQTLNQMLV EMDGFEGNEG IIVIAATNRP DVLDPALLRP GRFDRQVVVG LPDVRGREQI LKVHMRRVPL APDIDAAIIA RGTPGFSGAD LANLVNEAAL FAARGNKRVV SMVEFEKAKD KIMMGAERRS MVMTEAQKES TAYHEAGHAI IGRLVPEHDP VHKVTIIPRG RALGVTFFLP EGDAISASRQ KLESQISTLY GGRLAEEIIY GPEHVSTGAS NDIKVATNLA RNMVTQWGFS EKLGPLLYAE EEGEVFLGRS VAKAKHMSDE TARIIDQEVK ALIERNYNRA RQLLTDNMDI LHAMKDALMK YETIDAPQID DLMARRDVRP PAGWEEPGAS NNSGDNGSPK APRPVDEPRT PNPGNTMSEQ LGDK Bacterial inner membrane;Cytoplasm;Periplasmic space 92 Fusion PhoA 274 2999794 Fusion PhoA 293 2999794 Fusion PhoA 442 2999794 Fusion PhoA 383 2999794 Fusion PhoA 431 2999794 Fusion PhoA 416 2999794 Fusion PhoA 397 2999794 Fusion PhoA 367 2999794 Fusion PhoA 424 2999794 Structure PDBTM Structure PDBTM Immunolocalisation J Bacteriol 1993 Mar;175(5):1352-7 Acta Crystallogr D Biol Crystallogr. 2002 Jun;58(Pt 6 Pt 2):1066-7. Epub Structure. 2002 Aug;10(8):1073-83. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Peptidoglycan synthetase ftsI precursor Escherichia coli P04286 P0AD69 P0AD68 MKAAAKTQKP KRQEEHANFI SWRFALLCGC ILLALAFLLG RVAWLQVISP DMLVKEGDMR SLRVQQVSTS RGMITDRSGR PLAVSVPVKA IWADPKEVHD AGGISVGDRW KALANALNIP LDQLSARINA NPKGRFIYLA RQVNPDMADY IKKLKLPGIH LREESRRYYP SGEVTAHLIG FTNVDSQGIE GVEKSFDKWL TGQPGERIVR KDRYGRVIED ISSTDSQAAH NLALSIDERL QALVYRELNN AVAFNKAESG SAVLVDVNTG EVLAMANSPS YNPNNLSGTP KEAMRNRTIT DVFEPGSTVK PMVVMTALQR GVVRENSVLN TIPYRINGHE IKDVARYSEL TLTGVLQKSS NVGVSKLALA MPSSALVDTY SRFGLGKATN LGLVGERSGL YPQKQRWSDI ERATFSFGYG LMVTPLQLAR VYATIGSYGI YRPLSITKVD PPVPGERVFP ESIVRTVVHM MESVALPGGG GVKAAIKGYR IAIKTGTAKK VGPDGRYINK YIAYTAGVAP ASQPRFALVV VINDPQAGKY YGGAVSAPVF GAIMGGVLRT MNIEPDALTT GDKNEFVINQ GEGTGGRS Bacterial inner membrane;Cytoplasm;Periplasmic space 96 Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM Fusion BlaM 35 yes Fusion BlaM Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM 35 yes Fusion BlaM Fusion BlaM 35 yes Fusion BlaM Mol Microbiol 1989 Sep;3(9):1277-86 The beta-lactamase fusion points are taken from the figure 3, therefore are not exact (plus-minus 3 amino acid). It is indicated with the Approx="yes" tag. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License General secretion pathway protein N, OutN Pectobacterium carotovorum subsp. carotovorum P31710 MKLKSGIVTG VALVLAYGLF LASYAPARLL TAVPLPAGMV VAEAAGTLWQ GSLQRFSWRT LTLDDVHWNI TFSDFMPALD IAFKNPEGIA GRGIIRGWQR AQFYQWQLSV PAGYLFSHMR FIVPIGAEGN VQLNLQEATV DRSGCQSLDA NVTWPGARVK TPLGGLVLAT PQATLRCQQG ALEANLRQTS SHLQLSGKGS VTPKGEYRFT GQLSSGNDLP ATMKKLLATT GKANEQGART LNFQGRLL Bacterial inner membrane;Cytoplasm;Periplasmic space 76 Fusion BlaM 5 Fusion BlaM 160 Fusion BlaM 160 Fusion BlaM 80 Fusion BlaM 160 Fusion BlaM 160 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 160 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 80 Mol Microbiol 1994 May;12(3):445-57 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License General secretion pathway protein N, XcpP Pseudomonas aeruginosa Q51575 Q9HZB3 MIPRRSSDIT IKTRSDVLPF SGASSRWLQR YAPALLAVAL IIAMSISLAW QAAGWLRLQR SPVAVAASPV SHESIRSDPT RLARLFGTSA QDPNAPPPAT NLDLVLKGSF VQSDPKLSSA IIQRQGDKPH RYAVGGEISD GVKLHAVYRD RVELQRGGRL ESLPFPHRSG GLLASADDIT SENDSIEQLQ SLQDENAAAL RERLDALRQQ MEATPIAEPA EEDSSEPTTT PTESD Bacterial inner membrane;Cytoplasm;Periplasmic space 75 Fusion PhoA J Bacteriol 1996 Jul;178(14):4297-300 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Hemolysin secretion protein D, HlyD Escherichia coli P06739 MKTWLMGFSE FLLRYKLVWS ETWKIRKQLD TPVREKDENE FLPAHLELIE TPVSRRPRLV AYFIMGFLVI AFILSVLGQV EIVATANGKL THSGRSKEIK PIENSIVKEI IVKEGESVRK GDVLLKLTAL GAEADTLKTQ SSLLQARLEQ TRYQILSRSI ELNKLPELKL PDEPYFQNVS EEEVLRLTSL IKEQFSTWQN QKYQKELNLD KKRAERLTVL ARINRYENLS RVEKSRLDDF SSLLHKQAIA KHAVLEQENK YVEAVNELRV YKSQLEQIES EILSAKEEYQ LVTQLFKNEI LDKLRQTTDN IGLLTLELAK NEERQQASVI RAPVSVKVQQ LKVHTEGGVV TTAETLMVIV PEDDTLEVTA LVQNKDIGFI NVGQNAIIKV EAFPYTRYGY LVGKVKNINL DAIEDQRLGL VFNVIISIEE NCLSTGNKNI PLSSGMAVTA EIKTGMRSVI SYLLSPLEES VTESLRER Bacterial inner membrane;Cytoplasm;Periplasmic space 95 Fusion LacZ 1036 M1971 Fusion PhoA 3 1100846 Fusion LacZ 1343 M1971 Fusion BlaM 5 yes Fusion BlaM 5 yes Fusion BlaM 5 yes Fusion PhoA 579 1100846 Fusion PhoA 515 1100846 Fusion PhoA 510 1100846 Fusion PhoA 402 1100846 Fusion PhoA 456 1100846 Fusion PhoA 382 1100846 Fusion PhoA 258 1100846 Fusion PhoA 176 1100846 Fusion BlaM 25 yes Fusion BlaM 25 yes Fusion BlaM 25 yes Fusion PhoA 120 1100846 Fusion PhoA 193 1100846 Fusion PhoA 159 1100846 Fusion PhoA 186 1100846 Fusion PhoA 110 1100846 Mol Gen Genet 1992 Jul;234(1):155-63 J Mol Biol 1991 Feb 5;217(3):441-54 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Mitochondrial import inner membrane translocase subunit TIM23 Saccharomyces cerevisiae P32897 D6W1J2 MSWLFGDKTP TDDANAAVGG QDTTKPKELS LKQSLGFEPN INNIISGPGG MHVDTARLHP LAGLDKGVEY LDLEEEQLSS LEGSQGLIPS RGWTDDLCYG TGAVYLLGLG IGGFSGMMQG LQNIPPNSPG KLQLNTVLNH ITKRGPFLGN NAGILALSYN IINSTIDALR GKHDTAGSIG AGALTGALFK SSKGLKPMGY SSAMVAAACA VWCSVKKRLL EK Mitochondrial inner membrane;Matrix;Inter membrane space 73 Immunolocalisation This experiment shows, that the N terminal is not in the matrix, but they did not investigate the possibility, that the protein links the two membranes: the outer and the inner mitochondria membranes Protease Partial Proteolysis (ProtK protease) Protease Partial Proteolysis (Tryp protease) Protease Partial Proteolysis (ProtK protease) Immunolocalisation Epitope Insertion (ETcm epitope) FEBS Lett 1994 Aug 1;349(2):222-8 Cell 2000 May 12;101(4):401-12 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Lactococcin A secretion protein lcnD Lactococcus lactis subsp. lactis Q00565 P0A3G6 P0A3G5 MFDKKLLESS ELYDKRYRNF STLIILPLFI LLVGGVIFTF FAHKELTVIS TGSIEPTKIV AKIQSTNANP IIENNLKEGE AVKENSLLLK YNGTPEQTQL SELLTQKKQA LDKKVQLDLL QRSLTNEKNE FPTADSFGYE KSFENYEAQV KSLEATIQKS NQAVEDQNKS TESQKQAIQN QVATLQQAIQ NYSEIENAVS SGGGVSQDNP YLSQYNSYQA QQATLEADLK NQKNPDETAK QAAKSQEESL KSQFLSGLAS SKDSLKSQIQ SFNVQESSLT GSNAYDNSQS SQILTLKSQA LSASNKEMTD LNSTLTDLET KISLQKQDDQ YSQVFAEQAG VLHVLPDILG MKKIPIGTPI AEIYPLLKSE TQVNLTSYIP STQISGMKVG QKVRFTVQQN LPQPEILTGI INQIDSAPTA FKEGNAYKVS ATTTINAKDL PNIRYGLQGK TVTIIGKKTY FNYFLDKIMG RGNQ Bacterial inner membrane;Cytoplasm;Periplasmic space 94 Fusion LacZ Fusion PhoA Fusion LacZ Fusion PhoA Fusion LacZ Fusion PhoA Fusion LacZ Fusion PhoA J Bacteriol 1996 Mar;178(6):1766-9 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Sodium/potassium-transporting ATPase beta-1 chain Canis familiaris P06583 MARGKAKEEG SWKKFIWNSE KKEFLGRTGG SWFKILLFYV IFYGCLAGIF IGTIQVMLLT ISEFKPTYQD RVAPPGLTQI PQIQKTEISF RPNDPKSYEE YVRNIVRFLE KYKDSAQKDE MIFEDCGNMP SEIKERGEFN NERGERKVCR FKLEWLGNCS GINDETYGYR DGKPCVLIKL NRVLGFKPKP PKNESLEAYP VMKYSPYVLP VQCTGKRDED KDRIGNVEYF GLGGYPGFPL QYYPYYGKLL QPKYLQPLLA VQFTNLTMDT EIRIECKAYG ENIGYSEKDR FQGRFDVKIE VKS Plasma membrane;Cytoplasm;Extracellular 99 PostTransMod NGlyc PostTransMod NGlyc Fusion LacZ 2 6310320 1 PostTransMod NGlyc Biochim Biophys Acta. 1988 Apr 28;954(1):50-7. J Biol Chem 1996 Nov 15;271(46):29312-20 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Chemotaxis motB protein Escherichia coli P09349 P0AF07 P0AF06 MKNQAHPIIV VKRRKAKSHG AAHGSWKIAY ADFMTAMMAF FLVMWLISIS SPKELIQIAE YFRTPLATAV TGGDRISNSE SPIPGGGDDY TQSQGEVNKQ PNIEELKKRM EQSRLRKLRG DLDQLIESDP KLRALRPHLK IDLVQEGLRI QIIDSQNRPM FRTGSADVEP YMRDILRAIA PVLNGIPNRI SLSGHTDDFP YASGEKGYSN WELSADRANA SRRELMVGGL DSGKVLRVVG MAATMRLSDR GPDDAVNRRI SLLVLNKQAE QAILHENAES QNEPVSALEK PEVAPQVSVP TMPSAEPR Bacterial inner membrane;Cytoplasm;Periplasmic space 96 Protease Partial Proteolysis (Tryp protease) Science 1988 Jan 15;239(4837):276-8 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Penicillin-binding protein 1B Escherichia coli P02919 P75664 3.09 XRAY According to 19458048/Fig1 MAGNDREPIG RKGKPTRPVK QKVSRRRYED DDDYDDYDDY EDEEPMPRKG KGKGKGRKPR GKRGWLWLLL KLAIVFAVLI AIYGVYLDQK IRSRIDGKVW QLAAAVYGRM VNLEPDMTIS KNEMVKLLEA TQYRQVSKMT RPGEFTVQAN SIEMIRRPFD FPDSKEGQVR ARLTFDGDHL ATIVNMENNR QFGFFRLDPR LITMISSPNG EQRLFVPRSG FPDLLVDTLL ATEDRHFYEH DGISLYSIGR AVLANLTAGR TVQGASTLTQ QLVKNLFLSS ERSYWRKANE AYMALIMDAR YSKDRILELY MNEVYLGQSG DNEIRGFPLA SLYYFGRPVE ELSLDQQALL VGMVKGASIY NPWRNPKLAL ERRNLVLRLL QQQQIIDQEL YDMLSARPLG VQPRGGVISP QPAFMQLVRQ ELQAKLGDKV KDLSGVKIFT TFDSVAQDAA EKAAVEGIPA LKKQRKLSDL ETAIVVVDRF SGEVRAMVGG SEPQFAGYNR AMQARRSIGS LAKPATYLTA LSQPKIYRLN TWIADAPIAL RQPNGQVWSP QNDDRRYSES GRVMLVDALT RSMNVPTVNL GMALGLPAVT ETWIKLGVPK DQLHPVPAML LGALNLTPIE VAQAFQTIAS GGNRAPLSAL RSVIAEDGKV LYQSFPQAER AVPAQAAYLT LWTMQQVVQR GTGRQLGAKY PNLHLAGKTG TTNNNVDTWF AGIDGSTVTI TWVGRDNNQP TKLYGASGAM SIYQRYLANQ TPTPLNLVPP EDIADMGVDY DGNFVCSGGM RILPVWTSDP QSLCQQSEMQ QQPSGNPFDQ SSQPQQQPQQ QPAQQEQKDS DGVAGWIKDM FGSN Bacterial inner membrane;Cytoplasm;Periplasmic space 98 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Mol Microbiol 1987 Jul;1(1):101-6 J Bacteriol 1997 Aug;179(15):4761-7 No numerical topology data No numerical data Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):8824-9. doi: Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome B6-F complex 4 kDa subunit Chlamydomonas reinhardtii Q42496 3.10 XRAY The extramembrane domains of cytochrome f and the Rieske protein lie on the luminal side. Nature 246 p414 (pmid:14647374). In PDBTM Rieske protein (Chain C) has Side1 location, luminal side correspond to Outside, therfore Side1 = Outside MAMSIAARSA CCGVAAPRSS TVRVAAARPA VRPSLRTAGQ KAAPSRGVAT KAVNELAMIA GEAEFIAGTA LTMVGMTLVG LAIGFVLLRV ESLVEEGKI Chloroplast thylakoid membrane;Stroma;Thylakoid space 95 Immunolocalisation Structure PDBTM Structure PDBTM Immunolocalisation Structure PDBTM J Biol Chem 1996 May 3;271(18):10667-71 J Biol Chem. 2002 Apr 5;277(14):12446-55. Epub 2002 Jan 16. Nature. 2003 Nov 27;426(6965):413-8. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Repressible alkaline phosphatase precursor Saccharomyces cerevisiae P11491 Q03374 D6VTA4 E9P949 MMTHTLPSEQ TRLVPGSDSS SRPKKRRISK RSKIIVSTVV CIGLLLVLVQ LAFPSSFALR SASHKKKNVI FFVTDGMGPA SLSMARSFNQ HVNDLPIDDI LTLDEHFIGS SRTRSSDSLV TDSAAGATAF ACALKSYNGA IGVDPHHRPC GTVLEAAKLA GYLTGLVVTT RITDATPASF SSHVDYRWQE DLIATHQLGE YPLGRVVDLL MGGGRSHFYP QGEKASPYGH HGARKDGRDL IDEAQSNGWQ YVGDRKNFDS LLKSHGENVT LPFLGLFADN DIPFEIDRDE KEYPSLKEQV KVALGALEKA SNEDKDSNGF FLMVEGSRID HAGHQNDPAS QVREVLAFDE AFQYVLEFAE NSDTETVLVS TSDHETGGLV TSRQVTASYP QYVWYPQVLA NATHSGEFLK RKLVDFVHEH KGASSKIENF IKHEILEKDL GIYDYTDSDL ETLIHLDDNA NAIQDKLNDM VSFRAQIGWT THGHSAVDVN IYAYANKKAT WSYVLNNLQG NHENTEVGQF LENFLELNLN EVTDLIRDTK HTSDFDATEI ASEVQHYDEY YHELTN Lysosomal membrane;Cytoplasm;Lysosome 84 Protease Partial Proteolysis (ProtK protease) Protease Partial Proteolysis (ProtK protease) EMBO J 1989 Aug;8(8):2241-50 Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License HokC protein (Protein gef) Escherichia coli P22982 P75618 P0ACG4 Q2MCH5 P0ACG5 MKQHKAMIVA LIVICITAVV AALVTRKDLC EVHIRTGQTE VAVFTAYESE Bacterial inner membrane;Cytoplasm;Periplasmic space 69 Fusion PhoA Mol Microbiol 1991 Jul;5(7):1627-37 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Ribophorin I Homo sapiens P04843 B2R5Z0 D3DNB6 Q68DT1 MEAPAAGLFL LLLLGTWAPA PGSASSEAPP LINEDVKRTV DLSSHLAKVT AEVVLAHLGG GSTSRATSFL LALEPELEAR LAHLGVQVKG EDEEENNLEV RETKIKGKSG RFFTVKLPVA LDPGAKISVI VETVYTHVLH PYPTQITQSE KQFVVFEGNH YFYSPYPTKT QTMRVKLASR NVESYTKLGN PTRSEDLLDY GPFRDVPAYS QDTFKVHYEN NSPFLTITSM TRVIEVSHWG NIAVEENVDL KHTGAVLKGP FSRYDYQRQP DSGISSIRSF KTILPAAAQD VYYRDEIGNV STSHLLILDD SVEMEIRPRF PLFGGWKTHY IVGYNLPSYE YLYNLGDQYA LKMRFVDHVF DEQVIDSLTV KIILPEGAKN IEIDSPYEIS RAPDELHYTY LDTFGRPVIV AYKKNLVEQH IQDIVVHYTF NKVLMLQEPL LVVAAFYILF FTVIIYVRLD FSITKDPAAE ARMKVACITE QVLTLVNKRI GLYRHFDETV NRYKQSRDIS TLNSGKKSLE TEHKALTSEI ALLQSRLKTE GSDLCDRVSE MQKLDAQVKE LVLKSAVEAE RLVAGKLKKD TYIENEKLIS GKRQELVTKI DHILDAL Endoplasmic reticulum membrane;Cytoplasm;Cysternal space 80 PostTransMod NGlyc Protease Partial Proteolysis (Tryp protease) EMBO J 1987 Jan;6(1):75-82 J Proteome Res. 2009 Feb;8(2):651-61. doi: 10.1021/pr8008012. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Ribophorin II Homo sapiens P04844 Q9UBE1 Q5JYR6 Q6IBA5 Q96E21 Q9BUQ3 MAPPGSSTVF LLALTIIAST WALTPTHYLT KHDVERLKAS LDRPFTNLES AFYSIVGLSS LGAQVPDAKK ACTYIRSNLD PSNVDSLFYA AQASQALSGC EISISNETKD LLLAAVSEDS SVTQIYHAVA ALSGFGLPLA SQEALSALTA RLSKEETVLA TVQALQTASH LSQQADLRSI VEEIEDLVAR LDELGGVYLQ FEEGLETTAL FVAATYKLMD HVGTEPSIKE DQVIQLMNAI FSKKNFESLS EAFSVASAAA VLSHNRYHVP VVVVPEGSAS DTHEQAILRL QVTNVLSQPL TQATVKLEHA KSVASRATVL QKTSFTPVGD VFELNFMNVK FSSGYYDFLV EVEGDNRYIA NTVELRVKIS TEVGITNVDL STVDKDQSIA PKTTRVTYPA KAKGTFIADS HQNFALFFQL VDVNTGAELT PHQTFVRLHN QKTGQEVVFV AEPDNKNVYK FELDTSERKI EFDSASGTYT LYLIIGDATL KNPILWNVAD VVIKFPEEEA PSTVLSQNLF TPKQEIQHLF REPEKRPPTV VSNTFTALIL SPLLLLFALW IRIGANVSNF TFAPSTIIFH LGHAAMLGLM YVYWTQLNMF QTLKYLAILG SVTFLAGNRM LAQQAVKRTA H Endoplasmic reticulum membrane;Cytoplasm;Cysternal space 83 PostTransMod NGlyc PostTransMod NGlyc Protease Partial Proteolysis (Tryp protease) EMBO J 1987 Jan;6(1):75-82 J Proteome Res. 2009 Feb;8(2):651-61. doi: 10.1021/pr8008012. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Thromboxane-A synthase, TXS Homo sapiens P24557 Q16844 B4DJG6 E7EMU9 E7EP08 E7ESB5 O14987 Q16843 Q8IUN1 Q96CN2 Q9GZW4 Q9HD77 Q9HD78 Q9HD79 Q9HD80 Q9HD81 Q9HD82 Q9HD83 Q9HD84 MEALGFLKLE VNGPMVTVAL SVALLALLKW YSTSAFSRLE KLGLRHPKPS PFIGNLTFFR QGFWESQMEL RKLYGPLCGY YLGRRMFIVI SEPDMIKQVL VENFSNFTNR MASGLEFKSV ADSVLFLRDK RWEEVRGALM SAFSPEKLNE MVPLISQACD LLLAHLKRYA ESGDAFDIQR CYCNYTTDVV ASVAFGTPVD SWQAPEDPFV KHCKRFFEFC IPRPILVLLL SFPSIMVPLA RILPNKNRDE LNGFFNKLIR NVIALRDQQA AEERRRDFLQ MVLDARHSAS PMGVQDFDIV RDVFSSTGCK PNPSRQHQPS PMARPLTVDE IVGQAFIFLI AGYEIITNTL SFATYLLATN PDCQEKLLRE VDVFKEKHMA PEFCGLEEGL PYLDMVIAET LRMYPPAFRF TREAAQDCEV LGQRIPAGAV LEMAVGALHH DPEHWPSPET FNPERFTAEA RQQHRPFTYL PFGAGPRSCL GVRLGLLEVK LTLLHVLHKF RFQACPETQV PLQLESKSAL GPKNGVYIKI VSR Endoplasmic reticulum membrane;Cytoplasm;Cysternal space 78 Immunolocalisation J Biol Chem 1993 Sep 15;268(26):19483-90 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License TolR protein Escherichia coli P05829 P0ABV8 P0ABV6 P0ABV7 P0ABV9 MARARGRGRR DLKSEINIVP LLDVLLVLLL IFMATAPIIT QSVEVDLPDA TESQAVSSND NPPVIVEVSG IGQYTVVVEK DRLERLPPEQ VVAEVSSRFK ANPKTVFLIG GAKDVPYDEI IKALNLLHSA GVKSVGLMTQ PI Bacterial inner membrane;Cytoplasm;Periplasmic space 97 Fusion LacZ High Fusion LacZ High Fusion PhoA High Fusion PhoA High Fusion PhoA High Fusion PhoA High Protease Partial Proteolysis (ProtK protease) Fusion PhoA High Fusion PhoA High Fusion PhoA High Fusion PhoA High Fusion PhoA High Fusion PhoA High Fusion PhoA High Fusion PhoA High Fusion BlaM Fusion BlaM J Bacteriol 1993 Jul;175(14):4485-91 J Bacteriol 1993 Sep;175(18):6059-61 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License TonB protein Escherichia coli P02929 P76831 P94719 P94722 P94726 P94728 P94732 P94736 P94739 P97239 1.55 XRAY according to fig 4 (11328822) MTLDLPRRFP WPTLLSVCIH GAVVAGLLYT SVHQVIELPA PAQPISVTMV TPADLEPPQA VQPPPEPVVE PEPEPEPIPE PPKEAPVVIE KPKPKPKPKP KPVKKVQEQP KRDVKPVESR PASPFENTAP ARLTSSTATA ATSKPVTSVA SGPRALSRNQ PQYPARAQAL RIEGQVKVKF DVTPDGRVDN VQILSAKPAN MFEREVKNAM RRWRYEPGKP GSGIVVNILF KINGTTEIQ Bacterial inner membrane;Cytoplasm;Periplasmic space 82 Fusion PhoA 2 Fusion PhoA 83 Fusion PhoA 97 Fusion PhoA 71 Structure PDBTM Fusion PhoA 84 Fusion PhoA 95 J Bacteriol 1991 Sep;173(17):5554-7 J Biol Chem. 2001 Jul 20;276(29):27535-40. Epub 2001 Apr 27. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Infuenza Virus M2 Protein Influenza A virus (strain A/Bangkok/1/1979 H3N2) P03491 MSLLTEVETP IRNEWGCRCN DSSDPLVVAA SIIGILHLIL WILDRLFFKC IYRFFKHGLK RGPSTEGVPE SMREEYRKEQ QNAVDADDSH FVSIELE Plasma membrane;Cytoplasm;Extracellular 87 Protease Partial Proteolysis (Tryp protease) Immunolocalisation Immunolocalisation Cell 1985 Mar;40(3):627-33 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License NB glycoprotein Influenza B virus (strain B/Lee/1940) P06817 MNNATFNCTN INPITHIRGS IIITICVSLI VILIVFGCIA KIFINKNNCT NNVIRVHKRI KCPDCEPFCN KRDDISTPRA GVDIPSFILP GLNLSEGTPN Plasma membrane;Cytoplasm;Extracellular 94 Protease Partial Proteolysis (ProtK protease) PostTransMod NGlyc PostTransMod NGlyc Protease Partial Proteolysis (Tryp protease) Immunolocalisation Immunolocalisation Mol Cell Biol 1986 Dec;6(12):4317-28 J Gen Virol 1996 Nov;77 ( Pt 11):2689-94 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Nonstructural glycoprotein NCVP5, NS28 Rotavirus A (strain Cow/United States/NCDV-Lincoln/1969 G6-P6[1]-I2-R2-C2-M2-Ax-N2-T6-E2-Hx) P08434 MEKLTDLNYT SSVITLMNST LHTILEDPGM AYFPYIASVL TVLFTLHKAS IPTMKIALKT SKCSYKVVKY CIVTIFNTLL KLAGYKEQIT TKDEIEKQMD RVVKEMRRQL EMIDKLTTRE IEQVELLKRI HDKLMIRAVD EIDMTKEINQ KNVRTLEEWE NGKNPYEPKE VTAAM Endoplasmic reticulum membrane;Cytoplasm;Cysternal space 92 PostTransMod NGlyc PostTransMod NGlyc Protease Partial Proteolysis (Tryp protease) Protease Partial Proteolysis (ChyT protease) Protease Partial Proteolysis (V8 protease) EMBO J 1989 Jun;8(6):1695-703 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Sodium/potassium-transporting ATPase beta-1 chain Rattus norvegicus P07340 Q63062 MARGKAKEEG SWKKFIWNSE KKEFLGRTGG SWFKILLFYV IFYGCLAGIF IGTIQVMLLT ISELKPTYQD RVAPPGLTQI PQIQKTEISF RPNDPKSYEA YVLNIIRFLE KYKDSAQKDD MIFEDCGSMP SEPKERGEFN HERGERKVCR FKLDWLGNCS GLNDESYGYK EGKPCIIIKL NRVLGFKPKP PKNESLETYP LTMKYNPNVL PVQCTGKRDE DKDKVGNIEY FGMGGFYGFP LQYYPYYGKL LQPKYLQPLL AVQFTNLTLD TEIRIECKAY GENIGYSEKD RFQGRFDVKI EVKS Plasma membrane;Cytoplasm;Extracellular 99 Immunolocalisation Epitope Insertion (HAEI epitope) Permeabilized cells (with saponin) Immunolocalisation Epitope Insertion yes 95 (HAEI epitope) Non permeabilized cells Immunolocalisation Epitope Insertion yes 95 (HAEI epitope) Non permeabilized cells Immunolocalisation Epitope Insertion yes 95 (FETcm epitope) Non permeabilized cells J Biol Chem 1994 Nov 11;269(45):28249-58 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Photosystem I reaction centre subunit III precursor, PSI-F Synechococcus elongatus P0A402 P25899 2.50 XRAY PSI contains nine protein subunints featuring transmembrane alpha-helices (PsaA, PsaB, PsaE, PsaI, PsaJ, PsaK, PsaL, PsaM and PsaX) and three stromal subunits (PsaC, PsaD and PsaE) Nature. 2001 Jun 21;411(6840):910. PMID: 11418848. These three subunit are defined as Side1 in the corresponding PDBTM entry, therefore Side1=Inside. MRRFLALLLV LTLWLGFTPL ASADVAGLVP CKDSPAFQKR AAAAVNTTAD PASGQKRFER YSQALCGEDG LPHLVVDGRL SRAGDFLIPS VLFLYIAGWI GWVGRAYLIA VRNSGEANEK EIIIDVPLAI KCMLTGFAWP LAALKELASG ELTAKDNEIT VSPR Bacterial inner membrane;Cytoplasm;Periplasmic space 91 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Nat Struct Biol 1996 Nov;3(11):965-73. J Mol Biol 1997 Oct 10;272(5):741-69 J Biol Chem 1999 Mar 12;274(11):7351-60. J Biol Chem 1999 Mar 12;274(11):7361-7. Nature 2001 Jun 21;411(6840):909-17 XRAY structure Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Photosystem I reaction center subunit VIII, PSA-I Synechococcus elongatus P0A427 P25900 2.50 XRAY PSI contains nine protein subunints featuring transmembrane alpha-helices (PsaA, PsaB, PsaE, PsaI, PsaJ, PsaK, PsaL, PsaM and PsaX) and three stromal subunits (PsaC, PsaD and PsaE) Nature. 2001 Jun 21;411(6840):910. PMID: 11418848. These three subunit are defined as Side1 in the corresponding PDBTM entry, therefore Side1=Inside. 8.98 XRAY According to 11418848/Fig1 4.92 XRAY by similarity MMGSYAASFL PWIFIPVVCW LMPTVVMGLL FLYIEGEA Bacterial thylakoid membrane;Cytoplasm;Thylakoid space 88 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Nat Struct Biol 1996 Nov;3(11):965-73. J Mol Biol 1997 Oct 10;272(5):741-69. J Biol Chem 1999 Mar 12;274(11):7351-60. J Biol Chem 1999 Mar 12;274(11):7361-7. Nature 2001 Jun 21;411(6840):909-17 XRAY structure Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):213-21. doi: Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Photosystem I reaction center subunit IX, PSA-J Synechococcus elongatus P0A430 P25901 2.50 XRAY PSI contains nine protein subunints featuring transmembrane alpha-helices (PsaA, PsaB, PsaE, PsaI, PsaJ, PsaK, PsaL, PsaM and PsaX) and three stromal subunits (PsaC, PsaD and PsaE) Nature. 2001 Jun 21;411(6840):910. PMID: 11418848. These three subunit are defined as Side1 in the corresponding PDBTM entry, therefore Side1=Inside. MKHFLTYLST APVLAAIWMT ITAGILIEFN RFYPDLLFHP L Bacterial thylakoid membrane;Cytoplasm;Thylakoid space 89 Structure PDBTM Structure PDBTM Structure PDBTM Nat Struct Biol 1996 Nov;3(11):965-73. J Mol Biol 1997 Oct 10;272(5):741-69. J Biol Chem 1999 Mar 12;274(11):7351-60. J Biol Chem 1999 Mar 12;274(11):7361-7. Nature 2001 Jun 21;411(6840):909-17 XRAY structure Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Photosystem I reaction centre subunit XII, PSI-M Synechococcus elongatus P0A404 P25903 2.50 XRAY PSI contains nine protein subunints featuring transmembrane alpha-helices (PsaA, PsaB, PsaE, PsaI, PsaJ, PsaK, PsaL, PsaM and PsaX) and three stromal subunits (PsaC, PsaD and PsaE) Nature. 2001 Jun 21;411(6840):910. PMID: 11418848. These three subunit are defined as Side1 in the corresponding PDBTM entry, therefore Side1=Inside. MALTDTQVYV ALVIALLPAV LAFRLSTELY K Bacterial thylakoid membrane;Cytoplasm;Thylakoid space 91 Structure PDBTM Structure PDBTM Structure PDBTM Nat Struct Biol 1996 Nov;3(11):965-73. J Mol Biol 1997 Oct 10;272(5):741-69. J Biol Chem 1999 Mar 12;274(11):7351-60. J Biol Chem 1999 Mar 12;274(11):7361-7. Nature 2001 Jun 21;411(6840):909-17 XRAY structure Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Photosystem I reaction centre subunit PSI-X Thermosynechococcus elongatus (strain BP-1) Q8DKP6 2.50 XRAY PSI contains nine protein subunints featuring transmembrane alpha-helices (PsaA, PsaB, PsaE, PsaI, PsaJ, PsaK, PsaL, PsaM and PsaX) and three stromal subunits (PsaC, PsaD and PsaE) Nature. 2001 Jun 21;411(6840):910. PMID: 11418848. These three subunit are defined as Side1 in the corresponding PDBTM entry, therefore Side1=Inside. 8.98 XRAY According to 11418848/Fig1 4.92 XRAY by similarity ATKSAKPTYA FRTFWAVLLL AINFLVAAYY FAAAA Bacterial inner membrane;Cytoplasm;Periplasmic space 92 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Nat Struct Biol 1996 Nov;3(11):965-73. J Mol Biol 1997 Oct 10;272(5):741-69. J Biol Chem 1999 Mar 12;274(11):7351-60. J Biol Chem 1999 Mar 12;274(11):7361-7. Nature 2001 Jun 21;411(6840):909-17 XRAY structure Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):213-21. doi: Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Calcitonin receptor like receptor activity-modifying protein 1 precursor, RAMP1 Homo sapiens O60894 Q6FGS5 2.40 XRAY Crystal structure of the human receptor activity-modifying protein 1 extracellular domain. 2.80 XRAY Crystal structure of the ectodomain complex of the CGRP receptor 2.90 XRAY Crystal structure of the ectodomain complex of the CGRP receptor 2.10 XRAY Crystal structure of the ectodomain complex of the CGRP receptor MARALCRLPR RGLWLLLAHH LFMTTACQEA NYGALLRELC LTQFQVDMEA VGETLWCDWG RTIRSYRELA DCTWHMAEKL GCFWPNAEVD RFFLAVHGRY FRSCPISGRA VRDPPGSILY PFIVVPITVT LLVTALVVWQ SKRTEGIV Plasma membrane;Cytoplasm;Extracellular 96 Structure PDB Structure PDB Structure PDB Structure PDB Structure PDB Structure PDB Structure PDB Structure PDB Immunolocalisation Epitope Insertion (ETcm epitope) Structure PDB Nature 1998 May 28;393(6683):333-9 Protein Sci. 2008 Nov;17(11):1907-14. doi: 10.1110/ps.036012.108. Epub 2008 Aug Structure. 2010 Sep 8;18(9):1083-93. doi: 10.1016/j.str.2010.05.014. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License General secretion pathway protein G precursor, OutG Pectobacterium carotovorum subsp. carotovorum P31586 MQQSQRGCGQ NSYGQSGYRQ RGFTLLEIMV VIVILGVLAS LVVPNLMGNK EKADRQKAVS DIVSLESALD MYKLDNNRYP STEQGLKALV TKPTVQPEPR NYPADGYIRR LPQDPWGTDY QLLNPGQHGK LDIFSLGPDG MPGTEDDIGN WNLDKK Bacterial inner membrane;Cytoplasm;Periplasmic space 83 Fusion BlaM 5 Fusion BlaM 5 Fusion BlaM 5 Fusion BlaM 640 Fusion BlaM 640 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 1280 Mol Microbiol 1994 May;12(3):445-57 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License General secretion pathway protein H precursor, OutH Pectobacterium carotovorum subsp. carotovorum P31587 MKRSTRKQQG FTLLEMMLVV LLAGIAAGMV VMAFPPERQN DSAWQLARFQ AQLEFAAESS QVNEYMLGVR IYPDRWQFYQ LQRPAASERI PIPSGDRWQG YKWQPWQPHR VSASATLPEA LRLELLQADG KKVDKTQSGD DPDILILPGG EITPFRLLVK SENKALSNWL QVDNTGRFVT SMSQGKKR Bacterial inner membrane;Cytoplasm;Periplasmic space 83 Fusion BlaM 5 Fusion BlaM 320 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 80 Mol Microbiol 1994 May;12(3):445-57 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License General secretion pathway protein I precursor, OutI Pectobacterium carotovorum subsp. carotovorum P31588 MRRQKGMTLV EVLVALSVFA LAGIAVLQTT ARQASSLSRL EEKTFAGWVA ENQQVQLRLE QRWPEASWVR GETQFAGLRW HWRWQGVETG DPQTKALDVE VRRNKDAFAA DASLRTYVVK Q Bacterial inner membrane;Cytoplasm;Periplasmic space 91 Fusion BlaM 5 Fusion BlaM 160 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 80 Mol Microbiol 1994 May;12(3):445-57 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License General secretion pathway protein J precursor, OutJ Pectobacterium carotovorum subsp. carotovorum P31589 MSSKTGMCSQ TRRRREPARQ ERQQGFTLLE MILAIAIFAA LSLSAFQVLN GVMRNDEISQ RKAERLAEIQ RAFSQMDNDF SQMIARGSRG STSMFYAGRD QLKSDDWGVS FMRNGWQNPF GILPRSELQP VAYRLREHTL ERLTHVTPDP IEGLDPGVKP LLTQVDGFRL RFFSNKTWRD RWDNSTQLPQ GIEVVLTLRD YGEMSRMFLI TTGPVK Bacterial inner membrane;Cytoplasm;Periplasmic space 93 Fusion BlaM 160 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 35 Fusion BlaM 80 Mol Microbiol 1994 May;12(3):445-57 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License General secretion pathway protein L, XcpY Pseudomonas aeruginosa P25060 MSGVSALFLP PASTAGADGE LAVWWVQDGE CRRAPFAQAL AEIRAPWRLY LPVEAVTACA VNLPTQKARW LRQSLPFAVE EQLADDVEQM HLALGPALAD GRHRVFAVQR TWLAAWLALA EGAGKAPASL HVDADCLPGE GSCLFWLEER WLLGGSGAVR LACGSEDWPV LRDSCPPPQR AFAAQEVAPL EGVEVQALAG NPHVWLSEQP LGTDLAQAEF AARQQSSQWR RWRPLLGLVG LWLVLQWGFT LVQAWQLQRE GDRYAAQSAE LYRQLFPEDR KLINLRAQFD QHLADSASSG GEGQLLGLLG QAATVIGGEP TVSVEQLDFS AARGDVALQV RAPGFDVLER LRSRLSESGL AVQLGSASRD GSTVSARLVI GG Bacterial inner membrane;Cytoplasm;Periplasmic space 86 Fusion PhoA Fusion PhoA Fusion BlaM 500 J Bacteriol 1996 Jul;178(14):4297-300 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License General secretion pathway protein M, XcpZ Pseudomonas aeruginosa P25061 MKVMTQFHER LRAQAETSQL AIRWRGLPAR DRLALLWLGA FLLLVVLYLA LWRPAERHLQ SARQYFTEQR ALHAYIQQQA PNVRQADAAA PQAQIDPAAL QGMVTASAAQ AGLSVERLDN EGEGAVQVAL QPAPFAKLLP WLEQLNGQGV QVAEAGLDRQ VDGRVSARLS LRVE Bacterial inner membrane;Cytoplasm;Periplasmic space 89 Fusion PhoA Fusion BlaM 300 J Bacteriol 1996 Jul;178(14):4297-300 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License ATP synthase B chain Escherichia coli P00859 P0ABA2 P0ABA0 Q2M854 P0ABA1 P0ABA3 N/A NMR >>The alpha -helix from residues 27 to 33 may be part of a more extended alpha -helical segment of the cytoplasmic domain.<< This region is Side2 in PDBTM. J Biol Chem, Vol. 274, Issue 22, 15598-15604, May 28, 1999 1.55 XRAY ATP Synthase MNLNATILGQ AIAFVLFVLF CMKYVWPPLM AAIEKRQKEI ADGLASAERA HKDLDLAKAS ATDQLKKAKA EAQVIIEQAN KRRSQILDEA KAEAEQERTK IVAQAQAEIE AERKRAREEL RKQVAILAVA GAEKIIERSV DEAANSDIVD KLVAEL Bacterial inner membrane;Cytoplasm;Periplasmic space 94 Structure PDBTM Protease TID Structure PDBTM Protease TID Protease TID Protease TID Protease TID Protease TID Protease TID Protease TID Protease TID Protease TID Protease TID Protease TID Structure PDBTM Structure PDBTM Biochim Biophys Acta 1984 Apr 9;768(1):1-27 J Biol Chem 1999 May 28;274(22):15598-604 NMR structure Biochemistry. 2002 May 28;41(21):6875-84. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Integral membrane peripheral light harvesting complex from Rhodoblastus acidophilus P26789 2.5 XRAY >>alpha Trp45 the periplasmic key residue is also involved in B850 Bchl a coordination.<< J Mol Biol 1997 May 2;268(2):412-23. Trp45 is Side1 in PDBTM therefore Side1=Outside 2.00 XRAY >>The cytoplasmic surface (N terminus) is at the bottom of (c) and (d) where glucoside head groups of the first carotenoid (RG1) are located while at the periplasmic surface (C terminus, top ((a) and (d)) are located the glucosides of the second carotenoid (RG2).<< J Mol Biol 2003 Mar 7;326(5):1523-38. N-term: Side2 in PDBTM and C-term: Side1 in PDBTM. 2.45 XRAY >>The periplasmic surfaces in (a) and (b) are marked P: this surface is also the C-terminal surface of the peptides<< J Mol Biol. 2006 Apr 14;357(5):1605-18. This is Side1 in PDBTM. Therefore Side1=Outside. MNQGKIWTVV NPAIGIPALL GSVTVIAILV HLAILSHTTW FPAYWQGGVK KAA Unknown membrane;Unknown;Unknown 98 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure 1996 Apr 15;4(4):449-62 Curr Opin Struct Biol 1995 Dec;5(6):794-7. J Mol Biol 1997 May 2;268(2):412-23. J Mol Biol 2003 Mar 7;326(5):1523-38. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Mol Biol. 2006 Apr 14;357(5):1605-18. Epub 2006 Feb 2. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome c1, heme protein, mitochondrial (Cytochrome c-1) Bos taurus P00125 Q2TBM2 3.0 XRAY >>The mitochondrial targeting presequence of the >>Rieske<< protein (subunit 9) is lodged between the two >>core<< subunits at the matrix side of the complex.<< Science 1998 Jul 3;281(5373):64-71. Chain I is in Side2 in PDBTM. Therefore Side1=Outside. 3.0 XRAY >>The mitochondrial targeting presequence of the Rieske protein (subunit 9) is lodged between the two core subunits at the matrix side of the complex.<< Science 1998 Jul 3;281(5373):64-71. Chain I is in Side1 in PDBTM. Therfore Side1=Inside. 2.35 XRAY Sub 9 is in Matrix side on Figure 1 in Biochemistry. 2002 Oct 1;41(39):11692-702. This subunit are marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix side on Figure 1 in Biochemistry. 2002 Oct 1;41(39):11692-702. This subunit are marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.40 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 3.20 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.10 XRAY Sub 9 is in Matrix is marked as Side2 in PDBTM. Therefore Side1=Outside. 2.10 XRAY Sub 9 is in Matrix is marked as Side2 in PDBTM. Therefore Side1=Outside. 2.7 XRAY >>Both the NH2- and COOH-termini of the cytochrome b subunit are located in the mitochondrial matrix.<< Science. 1997 Jul 4;277(5322):60-6. This is Side1 in PDBTM. 2.69 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.70 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 3.00 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.85 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.10 XRAY Sub 9 is in Matrix and it is marked as Side2 in PDBTM. Therefore Side1=Outside. 2.26 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 19.00 XRAY by similarity SDLELHPPSY PWSHRGLLSS LDHTSIRRGF QVYKQVCSSC HSMDYVAYRH LVGVCYTEDE AKALAEEVEV QDGPNEDGEM FMRPGKLSDY FPKPYPNPEA ARAANNGALP PDLSYIVRAR HGGEDYVFSL LTGYCEPPTG VSLREGLYFN PYFPGQAIGM APPIYNEVLE FDDGTPATMS QVAKDVCTFL RWAAEPEHDH RKRMGLKMLL MMGLLLPLVY AMKRHKWSVL KSRKLAYRPP K Mitochondrial inner membrane;Matrix;Inter membrane space 98 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Science. 1997 Jul 4;277(5322):60-6. Science 1998 Jul 3;281(5373):64-71. Biochemistry. 2002 Oct 1;41(39):11692-702. Biochemistry 2003 Aug 5;42(30):9067-80. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Mol Biol. 2004 Jul 30;341(1):281-302. J Mol Biol. 2005 Aug 19;351(3):573-97. Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13045-50. Epub 2006 Aug 21. EMBO J. 2011 Sep 9;30(22):4652-64. doi: 10.1038/emboj.2011.324. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Ubiquinol-cytochrome c reductase iron-sulfur subunit, mitochondrial precursor (EC 1.10.2.2) (Rieske iron-sulfur protein) (RISP) [Contains: Ubiquinol-cytochrome c reductase 8 kDa protein (Complex III subunit IX)] Bos taurus P13272 A3KN53 P07588 Q1LZH6 3.0 XRAY >>The mitochondrial targeting presequence of the >>Rieske<< protein (subunit 9) is lodged between the two >>core<< subunits at the matrix side of the complex.<< Science 1998 Jul 3;281(5373):64-71. Chain I is in Side2 in PDBTM. Therefore Side1=Outside. 3.0 XRAY >>The mitochondrial targeting presequence of the Rieske protein (subunit 9) is lodged between the two core subunits at the matrix side of the complex.<< Science 1998 Jul 3;281(5373):64-71. Chain I is in Side1 in PDBTM. Therfore Side1=Inside. 2.35 XRAY Sub 9 is in Matrix side on Figure 1 in Biochemistry. 2002 Oct 1;41(39):11692-702. This subunit are marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix side on Figure 1 in Biochemistry. 2002 Oct 1;41(39):11692-702. This subunit are marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.40 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 3.20 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.10 XRAY Sub 9 is in Matrix is marked as Side2 in PDBTM. Therefore Side1=Outside. 2.10 XRAY Sub 9 is in Matrix is marked as Side2 in PDBTM. Therefore Side1=Outside. 2.7 XRAY >>Both the NH2- and COOH-termini of the cytochrome b subunit are located in the mitochondrial matrix.<< Science. 1997 Jul 4;277(5322):60-6. This is Side1 in PDBTM. 2.69 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.70 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 3.00 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.85 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.10 XRAY Sub 9 is in Matrix and it is marked as Side2 in PDBTM. Therefore Side1=Outside. 2.26 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 19.00 XRAY by similarity MLSVAARSGP FAPVLSATSR GVAGALRPLV QAAVPATSES PVLDLKRSVL CRESLRGQAA GRPLVASVSL NVPASVRYSH TDIKVPDFSD YRRPEVLDST KSSKESSEAR KGFSYLVTAT TTVGVAYAAK NVVSQFVSSM SASADVLAMS KIEIKLSDIP EGKNMAFKWR GKPLFVRHRT KKEIDQEAAV EVSQLRDPQH DLERVKKPEW VILIGVCTHL GCVPIANAGD FGGYYCPCHG SHYDASGRIR KGPAPLNLEV PSYEFTSDDM VIVG Mitochondrial inner membrane;Matrix;Inter membrane space 98 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Science. 1997 Jul 4;277(5322):60-6. Science 1998 Jul 3;281(5373):64-71. Biochemistry. 2002 Oct 1;41(39):11692-702. Biochemistry 2003 Aug 5;42(30):9067-80. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Mol Biol. 2004 Jul 30;341(1):281-302. J Mol Biol. 2005 Aug 19;351(3):573-97. Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13045-50. Epub 2006 Aug 21. EMBO J. 2011 Sep 9;30(22):4652-64. doi: 10.1038/emboj.2011.324. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C (EC 1.10.2.2) (Ubiquinol-cytochrome c reductase complex 9.5 kDa protein) (Complex III subunit VII) Bos taurus P13271 Q3ZBT9 3.0 XRAY >>The mitochondrial targeting presequence of the >>Rieske<< protein (subunit 9) is lodged between the two >>core<< subunits at the matrix side of the complex.<< Science 1998 Jul 3;281(5373):64-71. Chain I is in Side2 in PDBTM. Therefore Side1=Outside. 3.0 XRAY >>The mitochondrial targeting presequence of the Rieske protein (subunit 9) is lodged between the two core subunits at the matrix side of the complex.<< Science 1998 Jul 3;281(5373):64-71. Chain I is in Side1 in PDBTM. Therfore Side1=Inside. 2.35 XRAY Sub 9 is in Matrix side on Figure 1 in Biochemistry. 2002 Oct 1;41(39):11692-702. This subunit are marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix side on Figure 1 in Biochemistry. 2002 Oct 1;41(39):11692-702. This subunit are marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.40 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 3.20 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.10 XRAY Sub 9 is in Matrix is marked as Side2 in PDBTM. Therefore Side1=Outside. 2.10 XRAY Sub 9 is in Matrix is marked as Side2 in PDBTM. Therefore Side1=Outside. 2.7 XRAY >>Both the NH2- and COOH-termini of the cytochrome b subunit are located in the mitochondrial matrix.<< Science. 1997 Jul 4;277(5322):60-6. This is Side1 in PDBTM. 2.69 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.70 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 3.00 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.85 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.10 XRAY Sub 9 is in Matrix and it is marked as Side2 in PDBTM. Therefore Side1=Outside. 2.26 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 19.00 XRAY by similarity GRQFGHLTRV RHVITYSLSP FEQRAFPHYF SKGIPNVLRR TRACILRVAP PFVAFYLVYT WGTQEFEKSK RKNPAAYEND R Mitochondrial inner membrane;Matrix;Inter membrane space 94 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Science. 1997 Jul 4;277(5322):60-6. Science 1998 Jul 3;281(5373):64-71. Biochemistry. 2002 Oct 1;41(39):11692-702. Biochemistry 2003 Aug 5;42(30):9067-80. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Mol Biol. 2004 Jul 30;341(1):281-302. J Mol Biol. 2005 Aug 19;351(3):573-97. Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13045-50. Epub 2006 Aug 21. EMBO J. 2011 Sep 9;30(22):4652-64. doi: 10.1038/emboj.2011.324. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Ubiquinol-cytochrome c reductase complex 7.2 kDa protein (EC 1.10.2.2) (Cytochrome C1, nonheme 7 kDa protein) (Complex III subunit X) Bos taurus P00130 Q3SZT3 3.0 XRAY >>The mitochondrial targeting presequence of the >>Rieske<< protein (subunit 9) is lodged between the two >>core<< subunits at the matrix side of the complex.<< Science 1998 Jul 3;281(5373):64-71. Chain I is in Side2 in PDBTM. Therefore Side1=Outside. 3.0 XRAY >>The mitochondrial targeting presequence of the Rieske protein (subunit 9) is lodged between the two core subunits at the matrix side of the complex.<< Science 1998 Jul 3;281(5373):64-71. Chain I is in Side1 in PDBTM. Therfore Side1=Inside. 2.35 XRAY Sub 9 is in Matrix side on Figure 1 in Biochemistry. 2002 Oct 1;41(39):11692-702. This subunit are marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix side on Figure 1 in Biochemistry. 2002 Oct 1;41(39):11692-702. This subunit are marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.40 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 3.20 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.10 XRAY Sub 9 is in Matrix is marked as Side2 in PDBTM. Therefore Side1=Outside. 2.10 XRAY Sub 9 is in Matrix is marked as Side2 in PDBTM. Therefore Side1=Outside. 2.7 XRAY >>Both the NH2- and COOH-termini of the cytochrome b subunit are located in the mitochondrial matrix.<< Science. 1997 Jul 4;277(5322):60-6. This is Side1 in PDBTM. 2.69 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.70 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 3.00 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.85 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.10 XRAY Sub 9 is in Matrix and it is marked as Side2 in PDBTM. Therefore Side1=Outside. 2.26 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 19.00 XRAY by similarity VAPTLTARLY SLLFRRTSTF ALTIVVGALF FERAFDQGAD AIYEHINEGK LWKHIKHKYE NK Mitochondrial inner membrane;Matrix;Inter membrane space 94 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Science. 1997 Jul 4;277(5322):60-6. Science 1998 Jul 3;281(5373):64-71. Biochemistry. 2002 Oct 1;41(39):11692-702. Biochemistry 2003 Aug 5;42(30):9067-80. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Mol Biol. 2004 Jul 30;341(1):281-302. J Mol Biol. 2005 Aug 19;351(3):573-97. Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13045-50. Epub 2006 Aug 21. EMBO J. 2011 Sep 9;30(22):4652-64. doi: 10.1038/emboj.2011.324. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Glycophorin A precursor (PAS-2) (Sialoglycoprotein alpha) (MN sialoglycoprotein) (CD235a antigen) Homo sapiens P02724 A8K3E6 B8Q182 B8Q185 Q9BS51 N/A NMR Residues 62 to 71, which lie outside the membrane (5) and are unnecessary for dimerization (2), are poorly defined by this procedure N/A MODEL by similarity N/A NMR by similarity N/A NMR by similarity MYGKIIFVLL LSAIVSISAS STTGVAMHTS TSSSVTKSYI SSQTNDTHKR DTYAATPRAH EVSEISVRTV YPPEEETGER VQLAHHFSEP EITLIIFGVM AGVIGTILLI SYGIRRLIKK SPSDVKPLPS PDTDVPLSSV EIENPETSDQ Plasma membrane;Cytoplasm;Extracellular 86 PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc PostTransMod NGlyc Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Biochemistry 1992 Dec 29;31(51):12726-32. Glycobiology. 1993 Oct;3(5):429-35. J Biomol NMR 1996 May;7(3):256-60. Science 1997 Apr 4;276(5309):131-3. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Nat Methods. 2011 Oct 9;8(11):977-82. doi: 10.1038/nmeth.1731. Acta Naturae. 2011 Apr;3(2):90-8. Mol Cell Proteomics. 2013 Apr;12(4):932-44. doi: 10.1074/mcp.O112.021972. Epub EMBO J. 2013 May 15;32(10):1478-88. doi: 10.1038/emboj.2013.79. Epub 2013 Apr 12. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Reaction center protein H chain (Photosynthetic reaction center H subunit) Rhodobacter sphaeroides Q3J170 P11846 Q9RFD9 2.6 XRAY by similarity 2.2 XRAY by similarity 2.50 XRAY by similarity 2.50 XRAY by similarity 2.50 XRAY by similarity 2.7 XRAY by similarity 2.3 XRAY by similarity 2.80 XRAY by similarity 2.60 XRAY by similarity 2.60 XRAY by similarity 2.80 XRAY by similarity 3.01 XRAY by similarity 2.7 XRAY by similarity 2.7 XRAY by similarity 3.50 XRAY by similarity 3.10 XRAY by similarity 3.10 XRAY by similarity 2.50 XRAY by similarity 2.40 XRAY by similarity 3.25 XRAY >>The structure shows the cyt c2 to be positioned at the center of the periplasmic surface of the RC<< J Mol Biol. 2002 May 31;319(2):501-15. Chain C (cyt c) is marked as Side2 in PDBTM. Therefore Side1 is Inside. 2.55 XRAY by similarity 2.55 XRAY by similarity 2.35 XRAY by similarity 2.65 XRAY by similarity 3.0 XRAY by similarity 3.0 XRAY by similarity 2.1 XRAY by similarity 2.50 XRAY by similarity 2.80 XRAY by similarity 2.70 XRAY by similarity 2.75 XRAY by similarity 2.10 XRAY by similarity 1.80 XRAY by similarity 2.40 XRAY by similarity 2.60 XRAY by similarity 2.8 XRAY by similarity 2.25 XRAY by similarity 3.0 XRAY by similarity 4.50 XRAY by similarity 4.60 XRAY by similarity 2.7 XRAY by similarity 2.5 XRAY by similarity 2.4 XRAY by similarity 3.1 XRAY by similarity 2.8 XRAY by similarity MVGVTAFGNF DLASLAIYSF WIFLAGLIYY LQTENMREGY PLENEDGTPA ANQGPFPLPK PKTFILPHGR GTLTVPGPES EDRPIALART AVSEGFPHAP TGDPMKDGVG PASWVARRDL PELDGHGHNK IKPMKAAAGF HVSAGKNPIG LPVRGCDLEI AGKVVDIWVD IPEQMARFLE VELKDGSTRL LPMQMVKVQS NRVHVNALSS DLFAGIPTIK SPTEVTLLEE DKICGYVAGG LMYAAPKRKS VVAAMLAEYA Bacterial inner membrane;Cytoplasm;Periplasmic space 99 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Biochemistry 1992 May 12;31(18):4458-65. Biochemistry. 1991 Jun 4;30(22):5352-60. Biochemistry. 1991 Jun 4;30(22):5361-9. Annu Rev Biochem 1989;58:607-33. Proc Natl Acad Sci U S A 1987 Sep;84(17):6162-6. Proc Natl Acad Sci U S A 1986 Nov;83(22):8589-93. Proc Natl Acad Sci U S A 1988 Nov;85(22):8487-91. Proc Natl Acad Sci U S A 1988 Dec;85(23):9012-6. Proc Natl Acad Sci U S A 1988 Nov;85(21):7993-7. Proc Natl Acad Sci U S A 1987 Aug;84(16):5730-4. Proc Natl Acad Sci U S A 1987 Sep;84(18):6438-42. J Mol Biol. 1987 Jan 20;193(2):419-21. Proc Natl Acad Sci U S A 1984 Aug;81(15):4795-9. Biochemistry 1995 Jun 27;34(25):7967-72. Structure. 1994 Oct 15;2(10):925-36. Proc Natl Acad Sci U S A 1994 Oct 25;91(22):10265-9. Biochemistry 1996 May 28;35(21):6612-9. Science 1997 May 2;276(5313):812-6. Biochemistry 1998 Apr 7;37(14):4740-50. Biochemistry 1998 Jun 9;37(23):8278-81. Proc Natl Acad Sci U S A 1999 May 25;96(11):6183-8. Proc Natl Acad Sci U S A 1999 Dec 21;96(26):14706-11. Proc Natl Acad Sci U S A 2000 Feb 15;97(4):1542-7. Biochemistry 2000 May 23;39(20):5953-60. Biochem J 2000 Nov 1;351 Pt 3:567-78. Biochemistry 2001 Apr 10;40(14):4253-60. Biochemistry 2002 May 14;41(19):5998-6007. J Mol Biol 2002 May 31;319(2):501-15. Proc Natl Acad Sci U S A 2002 Aug 20;99(17):11055-60. Epub 2002 Aug 7. J Mol Biol 2003 Aug 15;331(3):681-92. Biochim Biophys Acta. 2004 Jan 30;1608(1):11-22. Structure. 2004 Apr;12(4):703-15. Structure. 2004 May;12(5):765-73. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Biochemistry. 2005 May 10;44(18):6920-8. Biochemistry. 2005 May 24;44(20):7389-94. Nat Struct Mol Biol. 2005 Jul;12(7):630-1. Epub 2005 Jun 5. Photosynth Res 2002;74(1):87-93. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Ubiquinol-cytochrome c reductase complex 6.4 kDa protein (EC 1.10.2.2) (Complex III subunit XI) Bos taurus P07552 A1A4P1 O18996 Q3T176 3.0 XRAY >>The mitochondrial targeting presequence of the >>Rieske<< protein (subunit 9) is lodged between the two >>core<< subunits at the matrix side of the complex.<< Science 1998 Jul 3;281(5373):64-71. Chain I is in Side2 in PDBTM. Therefore Side1=Outside. 2.35 XRAY Sub 9 is in Matrix side on Figure 1 in Biochemistry. 2002 Oct 1;41(39):11692-702. This subunit are marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix side on Figure 1 in Biochemistry. 2002 Oct 1;41(39):11692-702. This subunit are marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.40 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 3.20 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.7 XRAY >>Both the NH2- and COOH-termini of the cytochrome b subunit are located in the mitochondrial matrix.<< Science. 1997 Jul 4;277(5322):60-6. This is Side1 in PDBTM. 2.69 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.70 XRAY Sub 9 is in Matrix is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.60 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 2.26 XRAY Sub 9 is in Matrix and it is marked as Side1 in PDBTM. Therefore Side1=Inside. 19.00 XRAY by similarity MLTRFLGPRY RQLARNWVPT ASLWGAVGAV GLVWATDWRL ILDWVPYING KFKKDD Mitochondrial inner membrane;Matrix;Inter membrane space 97 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Science. 1997 Jul 4;277(5322):60-6. Science 1998 Jul 3;281(5373):64-71. Biochemistry. 2002 Oct 1;41(39):11692-702. Biochemistry 2003 Aug 5;42(30):9067-80. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Mol Biol. 2004 Jul 30;341(1):281-302. Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13045-50. Epub 2006 Aug 21. EMBO J. 2011 Sep 9;30(22):4652-64. doi: 10.1038/emboj.2011.324. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Coat protein B precursor (Major coat protein) Enterobacteria phage M13 P69541 P03617 N/A NMR fig 10 N/A NMR fig 10 MKKSLVLKAS VAVATLVPML SFAAEGDDPA KAAFNSLQAS ATEYIGYAWA MVVVIVGATI GIKLFKKFTS KAS Bacteriophage procoat protein (membrane insertion);Cytoplasm;Periplasmic space 90 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Eur J Biochem 1995 Sep 1;232(2):490-500. Biochemistry 1994 Nov 8;33(44):12990-7. Biochemistry 1993 Aug 17;32(32):8322-8. Biochemistry 1997 Apr 1;36(13):4015-26. J Mol Biol 1998 Sep 18;282(2):401-19. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Delta-hemolysin precursor (Delta-toxin) (Delta-lysin) Staphylococcus aureus P0C1V1 P01506 P0A0M3 N/A MODEL According to fig 2 (2281085) N/A NMR According to fig 2 (2281085) N/A MODEL According to fig 2 (2281085) N/A NMR According to fig 2 (2281085) N/A MODEL According to fig 2 (2281085) MMSCLILRIF ILIKEGVISM AQDIISTIGD LVKWIIDTVN KFTKK Toxin (membrane pore forming);Unknown;Unknown 73 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Biochem Soc Trans 1992 Nov;20(4):862-4. Proteins. 1990;8(3):213-25. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Light-harvesting protein B-875, beta chain (LH-3A) (Antenna pigment protein, beta chain) Rhodobacter sphaeroides P02951 P0C0Y1 Q3J1A3 N/A NMR >>N-terminal helix must lie in the lipid head groups or in the cytoplasm<< J Mol Biol. 2000 Apr 21;298(1):83-94. This region is assigned as Side2 in PDBTM. N/A NMR by similarity ADKSDLGYTG LTDEQAQELH SVYMSGLWLF SAVAIVAHLA VYIWRPWF Bacterial inner membrane;Cytoplasm;Periplasmic space 90 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM J Mol Biol 2000 Apr 21;298(1):83-94. Biochemistry 2002 Jan 8;41(1):31-41. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Reaction center protein H chain (Photosynthetic reaction center H subunit) Blastochloris viridis P06008 2.0 XRAY Chain C (cyt c2) is periplasmic and it is assigned as Side2 in PDBTM. Therefore Side1 is Inside 2.3 XRAY Chain C (cyt c2) is periplasmic and it is assigned as Side2 in PDBTM. Therefore Side1 is Inside 2.86 XRAY Chain C (cyt c2) is periplasmic and it is assigned as Side1 in PDBTM. Therefore Side1 is Outside 2.20 XRAY Chain C (cyt c2) is periplasmic and it is assigned as Side1 in PDBTM. Therefore Side1 is Outside 1.96 XRAY Chain C (cyt c2) is periplasmic and it is assigned as Side2 in PDBTM. Therefore Side1 is Inside 2.4 XRAY by similarity 2.45 XRAY Chain C (cyt c2) is periplasmic and it is assigned as Side2 in PDBTM. Therefore Side1 is Inside 1.95 XRAY According to 19743880/Fig1 1.86 XRAY According to 19743880/Fig1 3.00 XRAY According to 20431017/Fig1 3.00 XRAY According to 20431017/Fig1 3.21 XRAY by similarity 2.50 XRAY by similarity 2.40 XRAY Chain C (cyt c2) is periplasmic and it is assigned as Side2 in PDBTM. Therefore Side1 is Inside 1.95 XRAY by similarity 1.92 XRAY 22054235 ("In the LSP crystal structure of Blc. viridis RC (PDB code 2WJM) [10] a covalently bound lipid was found on the periplasmic side of membrane attached to the N-terminal cysteine residue of the cytochrome c subunit") 8.20 XRAY by similarity 3.50 XRAY by similarity 2.35 XRAY Chain C (cyt c2) is periplasmic and it is assigned as Side2 in PDBTM. Therefore Side1 is Inside 2.30 XRAY Chain C (cyt c2) is periplasmic and it is assigned as Side2 in PDBTM. Therefore Side1 is Inside 2.65 XRAY Chain C (cyt c2) is periplasmic and it is assigned as Side2 in PDBTM. Therefore Side1 is Inside MYHGALAQHL DIAQLVWYAQ WLVIWTVVLL YLRREDRREG YPLVEPLGLV KLAPEDGQVY ELPYPKTFVL PHGGTVTVPR RRPETRELKL AQTDGFEGAP LQPTGNPLVD AVGPASYAER AEVVDATVDG KAKIVPLRVA TDFSIAEGDV DPRGLPVVAA DGVEAGTVTD LWVDRSEHYF RYLELSVAGS ARTALIPLGF CDVKKDKIVV TSILSEQFAN VPRLQSRDQI TLREEDKVSA YYAGGLLYAT PERAESLL Bacterial inner membrane;Cytoplasm;Periplasmic space 99 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM J Mol Biol 1984 Dec 5;180(2):385-98. J Mol Biol 1982 Jul 5;158(3):567-72. J Mol Biol 1995 Feb 24;246(3):429-57. Structure. 1997 Oct 15;5(10):1339-59. J Mol Biol 1999 Feb 26;286(3):883-98. J Biol Chem 2000 Dec 15;275(50):39364-8. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5982-7. Epub 2004 Apr 8. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Am Chem Soc. 2004 Dec 29;126(51):16728-9. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19243-8. Epub 2006 Dec 11. J Am Chem Soc. 2008 Oct 29;130(43):14324-8. doi: 10.1021/ja805361j. Epub 2008 Oct Biochim Biophys Acta. 2009 Sep;1788(9):1822-31. doi: Biochemistry. 2009 Oct 20;48(41):9831-8. doi: 10.1021/bi900545e. Science. 2010 Apr 30;328(5978):630-3. doi: 10.1126/science.1186159. Biochem J. 2012 Feb 15;442(1):27-37. doi: 10.1042/BJ20111540. Nat Methods. 2012 Jan 29;9(3):263-5. doi: 10.1038/nmeth.1867. Nat Commun. 2013 Dec 19;4:2911. doi: 10.1038/ncomms3911. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome c oxidase polypeptide II (EC 1.9.3.1) (Cytochrome c ba(3) subunit II) (Cytochrome cba3 subunit 2) Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) Q5SJ80 2.40 XRAY >>All N-termini of the three subunits are on the cytoplasmic (negative) side of the membrane and all C-termini are on the periplasmic side.<< EMBO J. 2000 Apr 17;19(8):1766-76. These regions are marked as Side1 in PDBTM. 2.30 XRAY by similarity 1.6 XRAY >>The structure of the CuA-containing, extracellular domain of Thermus thermophilus ba3-type cytochrome c oxidase has been determined<< (10360350) 3.25 XRAY by similarity 2.90 XRAY by similarity 3.37 XRAY by similarity 3.10 XRAY by similarity 2.90 XRAY by similarity 2.80 XRAY by similarity 2.90 XRAY by similarity 3.20 XRAY by similarity 2.80 XRAY by similarity 2.95 XRAY by similarity 2.90 XRAY by similarity 2.80 XRAY by similarity 4.45 XRAY by similarity 4.20 XRAY by similarity 4.80 XRAY by similarity 4.25 XRAY by similarity 3.30 XRAY by similarity 4.00 XRAY by similarity 3.75 XRAY by similarity 1.80 XRAY According to 21814577/Fig3 1.80 XRAY According to 21814577/Fig3 2.50 XRAY by similarity 2.80 XRAY by similarity 2.60 XRAY by similarity 2.90 XRAY by similarity 3.19 XRAY by similarity 2.60 XRAY by similarity 3.05 XRAY by similarity N/A XRAY by similarity 2.80 XRAY by similarity 2.70 XRAY by similarity 2.80 XRAY by similarity MVDEHKAHKA ILAYEKGWLA FSLAMLFVFI ALIAYTLATH TAGVIPAGKL ERVDPTTVRQ EGPWADPAQA VVQTGPNQYT VYVLAFAFGY QPNPIEVPQG AEIVFKITSP DVIHGFHVEG TNINVEVLPG EVSTVRYTFK RPGEYRIICN QYCGLGHQNM FGTIVVKE Bacterial inner membrane;Cytoplasm;Periplasmic space 98 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Nat Struct Biol. 1999 Jun;6(6):509-16. EMBO J 2000 Apr 17;19(8):1766-76. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Acta Crystallogr D Biol Crystallogr. 2005 Mar;61(Pt 3):340-3. Epub 2005 Feb 24. Protein Expr Purif. 2005 Apr;40(2):299-318. PLoS One. 2011;6(7):e22348. doi: 10.1371/journal.pone.0022348. Epub 2011 Jul 21. To be published Biochim Biophys Acta. 2012 Apr;1817(4):658-65. doi: 10.1016/j.bbabio.2011.12.010. Biochemistry. 2012 Jun 12;51(23):4669-76. doi: 10.1021/bi3003988. Epub 2012 May Biochemistry. 2013 Jan 29;52(4):640-52. doi: 10.1021/bi301358a. Epub 2013 Jan 18. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome c oxidase polypeptide IIA (EC 1.9.3.1) (Cytochrome c ba(3) Subunit IIA) (Cytochrome cba3 subunit 2A) Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) P82543 Q5SJ81 2.40 XRAY >>All N-termini of the three subunits are on the cytoplasmic (negative) side of the membrane and all C-termini are on the periplasmic side.<< EMBO J. 2000 Apr 17;19(8):1766-76. These regions are marked as Side1 in PDBTM. 2.30 XRAY by similarity 3.25 XRAY by similarity 2.90 XRAY by similarity 3.37 XRAY by similarity 3.10 XRAY by similarity 2.90 XRAY by similarity 2.80 XRAY by similarity 2.90 XRAY by similarity 3.20 XRAY by similarity 2.80 XRAY by similarity 2.95 XRAY by similarity 2.90 XRAY by similarity 2.80 XRAY by similarity 4.45 XRAY by similarity 4.20 XRAY by similarity 4.80 XRAY by similarity 4.25 XRAY by similarity 3.30 XRAY by similarity 4.00 XRAY by similarity 3.75 XRAY by similarity 1.80 XRAY According to 21814577/Fig3 1.80 XRAY According to 21814577/Fig3 2.50 XRAY by similarity 2.80 XRAY by similarity 2.60 XRAY by similarity 2.90 XRAY by similarity 3.19 XRAY by similarity 2.60 XRAY by similarity 3.05 XRAY by similarity 2.00 XRAY by similarity 2.80 XRAY by similarity 2.70 XRAY by similarity 2.80 XRAY by similarity MEEKPKGALA VILVLTLTIL VFWLGVYAVF FARG Bacterial inner membrane;Cytoplasm;Periplasmic space 93 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM EMBO J 2000 Apr 17;19(8):1766-76. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Acta Crystallogr D Biol Crystallogr. 2005 Mar;61(Pt 3):340-3. Epub 2005 Feb 24. Protein Expr Purif. 2005 Apr;40(2):299-318. PLoS One. 2011;6(7):e22348. doi: 10.1371/journal.pone.0022348. Epub 2011 Jul 21. To be published Biochim Biophys Acta. 2012 Apr;1817(4):658-65. doi: 10.1016/j.bbabio.2011.12.010. Biochemistry. 2012 Jun 12;51(23):4669-76. doi: 10.1021/bi3003988. Epub 2012 May Biochemistry. 2013 Jan 29;52(4):640-52. doi: 10.1021/bi301358a. Epub 2013 Jan 18. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License H subunit of photosynthetic reaction center complex (Fragment) Thermochromatium tepidum Q93RD8 2.2 XRAY Cyt c is in periplasm ITHYIDAAQI TIWAFWLFFF GLIIYLRRED KREGYPLDSN RTERSGGRVK VVGFPDLPDP KTFVLPHNGG TVVAPRVEAP VAVNATPFSP APGSPLVPNG DPMLSGFGPA ACPDRPKHCD LTFEGLPKIV PMRVAKEFSI AEGDPDPRGM TVVGLDGEVA GTVSDVWVDR SEPQIRYLEV EVAANKKKVL LPIGFSRFDK KARKVKVDAI KAAHFANVPT LSNPDQVTLY EEDKVCAYYA GGKLYATAER AGPLL Bacterial inner membrane;Cytoplasm;Periplasmic space 99 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM FEBS Lett 1994 Jul 11;348(2):158-60. Proc Natl Acad Sci U S A 2000 Dec 5;97(25):13561-6. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome c1, heme protein, mitochondrial precursor Saccharomyces cerevisiae P07143 D6W2C8 2.30 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side1 in PDBTM. Threfore Side1 is Outside. 2.30 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side1 in PDBTM. Threfore Side1 is Outside. 2.97 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side2 in PDBTM. Threfore Side1 is Inside. 2.50 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side1 in PDBTM. Threfore Side1 is Outside. 2.30 XRAY by similarity 1.90 XRAY by similarity 2.50 XRAY by similarity 3.04 XRAY by similarity MFSNLSKRWA QRTLSKSFYS TATGAASKSG KLTQKLVTAG VAAAGITAST LLYADSLTAE AMTAAEHGLH APAYAWSHNG PFETFDHASI RRGYQVYREV CAACHSLDRV AWRTLVGVSH TNEEVRNMAE EFEYDDEPDE QGNPKKRPGK LSDYIPGPYP NEQAARAANQ GALPPDLSLI VKARHGGCDY IFSLLTGYPD EPPAGVALPP GSNYNPYFPG GSIAMARVLF DDMVEYEDGT PATTSQMAKD VTTFLNWCAE PEHDERKRLG LKTVIILSSL YLLSIWVKKF KWAGIKTRKF VFNPPKPRK Mitochondrial inner membrane;Matrix;Inter membrane space 98 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure Fold Des 2000 Jun 15;8(6):669-84. EMBO J 2001 Dec 3;20(23):6591-600. Proc Natl Acad Sci U S A 2002 Mar 5;99(5):2800-5. J Biol Chem 2003 Aug 15;278(33):31303-11. Epub 2003 Jun 2. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Mol Biol. 2007 Feb 11; [Epub ahead of print] J Biol Chem. 2008 Jun 20;283(25):17542-9. doi: 10.1074/jbc.M710126200. Epub 2008 Nat Commun. 2014 Jun 4;5:4029. doi: 10.1038/ncomms5029. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Ubiquinol-cytochrome c reductase iron-sulfur subunit, mitochondrial precursor (EC 1.10.2.2) (Rieske iron-sulfur protein) (RISP) Saccharomyces cerevisiae P08067 D3DLM4 2.30 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side1 in PDBTM. Threfore Side1 is Outside. 2.30 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side1 in PDBTM. Threfore Side1 is Outside. 2.97 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side2 in PDBTM. Threfore Side1 is Inside. 2.50 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side1 in PDBTM. Threfore Side1 is Outside. 2.30 XRAY by similarity 1.90 XRAY by similarity 2.50 XRAY by similarity 3.04 XRAY by similarity MLGIRSSVKT CFKPMSLTSK RLISQSLLAS KSTYRTPNFD DVLKENNDAD KGRSYAYFMV GAMGLLSSAG AKSTVETFIS SMTATADVLA MAKVEVNLAA IPLGKNVVVK WQGKPVFIRH RTPHEIQEAN SVDMSALKDP QTDADRVKDP QWLIMLGICT HLGCVPIGEA GDFGGWFCPC HGSHYDISGR IRKGPAPLNL EIPAYEFDGD KVIVG Mitochondrial inner membrane;Matrix;Inter membrane space 98 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure Fold Des 2000 Jun 15;8(6):669-84. EMBO J 2001 Dec 3;20(23):6591-600. Proc Natl Acad Sci U S A 2002 Mar 5;99(5):2800-5. J Biol Chem 2003 Aug 15;278(33):31303-11. Epub 2003 Jun 2. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Mol Biol. 2007 Feb 11; [Epub ahead of print] J Biol Chem. 2008 Jun 20;283(25):17542-9. doi: 10.1074/jbc.M710126200. Epub 2008 Nat Commun. 2014 Jun 4;5:4029. doi: 10.1038/ncomms5029. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C (EC 1.10.2.2) (Ubiquinol-cytochrome c reductase complex 11 kDa protein) (Complex III subunit VIII) Saccharomyces cerevisiae P08525 D6VW21 2.30 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side1 in PDBTM. Threfore Side1 is Outside. 2.30 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side1 in PDBTM. Threfore Side1 is Outside. 2.97 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side2 in PDBTM. Threfore Side1 is Inside. 2.50 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side1 in PDBTM. Threfore Side1 is Outside. 2.30 XRAY by similarity 1.90 XRAY by similarity 2.50 XRAY by similarity 3.04 XRAY by similarity MGPPSGKTYM GWWGHMGGPK QKGITSYAVS PYAQKPLQGI FHNAVFNSFR RFKSQFLYVL IPAGIYWYWW KNGNEYNEFL YSKAGREELE RVNV Mitochondrial inner membrane;Matrix;Inter membrane space 95 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure Fold Des 2000 Jun 15;8(6):669-84. EMBO J 2001 Dec 3;20(23):6591-600. Proc Natl Acad Sci U S A 2002 Mar 5;99(5):2800-5. J Biol Chem 2003 Aug 15;278(33):31303-11. Epub 2003 Jun 2. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Mol Biol. 2007 Feb 11; [Epub ahead of print] J Biol Chem. 2008 Jun 20;283(25):17542-9. doi: 10.1074/jbc.M710126200. Epub 2008 Nat Commun. 2014 Jun 4;5:4029. doi: 10.1038/ncomms5029. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Ubiquinol-cytochrome c reductase complex 7.3 kDa protein (EC 1.10.2.2) (Complex III polypeptide IX) Saccharomyces cerevisiae P22289 D6VUW6 2.30 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side1 in PDBTM. Threfore Side1 is Outside. 2.30 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side1 in PDBTM. Threfore Side1 is Outside. 2.97 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side2 in PDBTM. Threfore Side1 is Inside. 2.50 XRAY Rieske protein (chain E) is in intermembrane space and it is marked as Side1 in PDBTM. Threfore Side1 is Outside. 2.30 XRAY by similarity 1.90 XRAY by similarity 2.50 XRAY by similarity 3.04 XRAY by similarity SFSSLYKTFF KRNAVFVGTI FAGAFVFQTV FDTAITSWYE NHNKGKLWKD VKARIAAGDG DDDDE Mitochondrial inner membrane;Matrix;Inter membrane space 95 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure Fold Des 2000 Jun 15;8(6):669-84. EMBO J 2001 Dec 3;20(23):6591-600. Proc Natl Acad Sci U S A 2002 Mar 5;99(5):2800-5. J Biol Chem 2003 Aug 15;278(33):31303-11. Epub 2003 Jun 2. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Mol Biol. 2007 Feb 11; [Epub ahead of print] J Biol Chem. 2008 Jun 20;283(25):17542-9. doi: 10.1074/jbc.M710126200. Epub 2008 Nat Commun. 2014 Jun 4;5:4029. doi: 10.1038/ncomms5029. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Coat protein B precursor (Major coat protein) Enterobacteria phage fd P69539 N/A NMR by similarity MKKSLVLKAS VAVATLVPML SFAAEGDDPA KAAFDSLQAS ATEYIGYAWA MVVVIVGATI GIKLFKKFTS KAS Bacteriophage procoat protein (membrane insertion);Cytoplasm;Periplasmic space 90 Structure PDBTM Structure PDBTM Structure PDBTM J Mol Biol 1997 Jul 18;270(3):481-95. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cardiac phospholamban (PLB) Sus scrofa P61013 P07473 N/A NMR by similarity N/A NMR by similarity N/A MODEL by similarity N/A MODEL >>The N-terminal cytoplasmic portion of WT-PLB has a net charge of +3 with the posttranslational acetylation<< J. Biol. Chem., Vol. 276, Issue 42, 38814-38819 This region is assigned as Side1 in PDBTM. MDKVQYLTRS AIRRASTIEM PQQARQNLQN LFINFCLILI CLLLICIIVM LL Plasma membrane;Cytoplasm;Extracellular 89 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Biochemistry 1998 Sep 1;37(35):12074-81. J Biol Chem 2001 Oct 19;276(42):38814-9. Epub 2001 Jul 26. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.1.112) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Epidermal growth factor receptor-related protein) Rattus norvegicus P06494 Q6P732 N/A NMR by similarity 2.40 XRAY Structure of the extracellular region of HER2 N/A MODEL ErbB receptors are composed of an extracellular ligand-binding region, a transmembrane region and a cytoplasmic tyrosine kinase MELAAWCRWG FLLALLPPGI AGTQVCTGTD MKLRLPASPE THLDMLRHLY QGCQVVQGNL ELTYVPANAS LSFLQDIQEV QGYMLIAHNQ VKRVPLQRLR IVRGTQLFED KYALAVLDNR DPQDNVAAST PGRTPEGLRE LQLRSLTEIL KGGVLIRGNP QLCYQDMVLW KDVFRKNNQL APVDIDTNRS RACPPCAPAC KDNHCWGESP EDCQILTGTI CTSGCARCKG RLPTDCCHEQ CAAGCTGPKH SDCLACLHFN HSGICELHCP ALVTYNTDTF ESMHNPEGRY TFGASCVTTC PYNYLSTEVG SCTLVCPPNN QEVTAEDGTQ RCEKCSKPCA RVCYGLGMEH LRGARAITSD NVQEFDGCKK IFGSLAFLPE SFDGDPSSGI APLRPEQLQV FETLEEITGY LYISAWPDSL RDLSVFQNLR IIRGRILHDG AYSLTLQGLG IHSLGLRSLR ELGSGLALIH RNAHLCFVHT VPWDQLFRNP HQALLHSGNR PEEDLCVSSG LVCNSLCAHG HCWGPGPTQC VNCSHFLRGQ ECVEECRVWK GLPREYVSDK RCLPCHPECQ PQNSSETCFG SEADQCAACA HYKDSSSCVA RCPSGVKPDL SYMPIWKYPD EEGICQPCPI NCTHSCVDLD ERGCPAEQRA SPVTFIIATV VGVLLFLILV VVVGILIKRR RQKIRKYTMR RLLQETELVE PLTPSGAMPN QAQMRILKET ELRKVKVLGS GAFGTVYKGI WIPDGENVKI PVAIKVLREN TSPKANKEIL DEAYVMAGVG SPYVSRLLGI CLTSTVQLVT QLMPYGCLLD HVREHRGRLG SQDLLNWCVQ IAKGMSYLED VRLVHRDLAA RNVLVKSPNH VKITDFGLAR LLDIDETEYH ADGGKVPIKW MALESILRRR FTHQSDVWSY GVTVWELMTF GAKPYDGIPA REIPDLLEKG ERLPQPPICT IDVYMIMVKC WMIDSECRPR FRELVSEFSR MARDPQRFVV IQNEDLGPSS PMDSTFYRSL LEDDDMGDLV DAEEYLVPQQ GFFSPDPTPG TGSTAHRRHR SSSTRSGGGE LTLGLEPSEE GPPRSPLAPS EGAGSDVFDG DLAMGVTKGL QSLSPHDLSP LQRYSEDPTL PLPPETDGYV APLACSPQPE YVNQSEVQPQ PPLTPEGPLP PVRPAGATLE RPKTLSPGKN GVVKDVFAFG GAVENPEYLV PREGTASPPH PSPAFSPAFD NLYYWDQNSS EQGPPPSNFE GTPTAENPEY LGLDVPV Plasma membrane;Cytoplasm;Extracellular 90 Structure PDBTM Structure PDBTM PostTransMod NGlyc Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Biochemistry 2001 May 29;40(21):6534-40. Nature. 2003 Feb 13;421(6924):756-60. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Mol Biol. 2006 Sep 1;361(5):945-53. Epub 2006 Aug 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Light-harvesting protein B-800/820, alpha chain (Antenna pigment protein, alpha chain) Rhodoblastus acidophilus P35089 3.00 XRAY by similarity MNQGKIWTVV PPAFGLPLML GAVAITALLV HAAVLTHTTW YAAFLQGGVK KAA Bacterial inner membrane;Cytoplasm;Periplasmic space 98 Structure PDBTM Structure PDBTM Structure PDBTM Biochemistry 2001 Jul 31;40(30):8783-9. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Light-harvesting protein B-800/820, beta chain (Antenna pigment protein, beta chain) Rhodoblastus acidophilus P35094 3.00 XRAY by similarity AEVLTSEQAE ELHKHVIDGT RVFLVIAAIA HFLAFTLTPW LH Bacterial inner membrane;Cytoplasm;Periplasmic space 98 Structure PDBTM Structure PDBTM Structure PDBTM Biochemistry 2001 Jul 31;40(30):8783-9. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome b559 alpha subunit (PSII reaction center subunit V) Thermosynechococcus elongatus (strain BP-1) Q8DIP0 3.70 XRAY Interactions among CP47, CP43, D1, D2, and the three extrinsic proteins 33 kDa, 12 kDa, and cyt c550 in the luminal region. Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):98-103. cyt 550 (chains V, 0) are marked as Side2 in PDBTM therefore Side1=Inside 3.50 XRAY Single copies of each of the three extrinsic proteins, PsbO, PsbU, and PsbV, are located on the lumenal surface Science. 2004 Mar 19;303(5665):1831-8. Chain V is marked as Side2 in PDBTM, therefore Side1=Inside 3.2 XRAY by similarity 3.00 XRAY according to fig 1 in 16355230 3.70 XRAY by similarity 4.00 XRAY by similarity 3.60 XRAY by similarity 3.20 XRAY by similarity 3.20 XRAY by similarity 6.56 XRAY by similarity 5.70 XRAY by similarity 5.90 XRAY by similarity 5.00 XRAY According to 25043005/Fig2 5.5 XRAY According to 21499260/Fig1 4.90 XRAY by similarity 4.60 XRAY by similarity 4.50 XRAY by similarity 5.2 XRAY by similarity AGTTGERPFS DIITSVRYWV IHSITIPALF IAGWLFVSTG LAYDVFGTPR PDSYYAQEQR SIPLVTDRFE AKQQVETFLE QLK Bacterial thylakoid membrane;Cytoplasm;Thylakoid space 96 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Proc Natl Acad Sci U S A 2003 Jan 7;100(1):98-103. Epub 2002 Dec 23. Science. 2004 Mar 19;303(5665):1831-8. Epub 2004 Feb 5. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Photosynth Res. 2005 Jun;84(1-3):153-9. Nature. 2005 Dec 15;438(7070):1040-4. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8567-72. doi: J Biol Chem. 2010 Aug 20;285(34):26255-62. doi: 10.1074/jbc.M110.127589. Epub J Biol Chem. 2011 May 6;286(18):15964-72. doi: 10.1074/jbc.M110.215970. Nature. 2011 May 5;473(7345):55-60. doi: 10.1038/nature09913. Epub 2011 Apr 17. Acta Crystallogr D Biol Crystallogr. 2012 Apr;68(Pt 4):352-67. doi: Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9721-6. doi: Science. 2013 Apr 26;340(6131):491-5. doi: 10.1126/science.1234273. Epub 2013 Feb Nature. 2014 Jul 9. doi: 10.1038/nature13453. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome b559 beta subunit (PSII reaction center subunit VI) Thermosynechococcus elongatus (strain BP-1) Q8DIN9 3.70 XRAY Interactions among CP47, CP43, D1, D2, and the three extrinsic proteins 33 kDa, 12 kDa, and cyt c550 in the luminal region. Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):98-103. cyt 550 (chains V, 0) are marked as Side2 in PDBTM therefore Side1=Inside 3.50 XRAY Single copies of each of the three extrinsic proteins, PsbO, PsbU, and PsbV, are located on the lumenal surface Science. 2004 Mar 19;303(5665):1831-8. Chain V is marked as Side2 in PDBTM, therefore Side1=Inside 3.2 XRAY by similarity 3.00 XRAY according to fig 1 in 16355230 3.70 XRAY by similarity 4.00 XRAY by similarity 3.60 XRAY by similarity 3.20 XRAY by similarity 3.20 XRAY by similarity 6.56 XRAY by similarity 5.70 XRAY by similarity 5.90 XRAY by similarity 5.00 XRAY According to 25043005/Fig2 5.5 XRAY According to 21499260/Fig1 4.90 XRAY by similarity 4.60 XRAY by similarity 4.50 XRAY by similarity 5.2 XRAY by similarity MTSNTPNQEP VSYPIFTVRW VAVHTLAVPT IFFLGAIAAM QFIQR Bacterial thylakoid membrane;Cytoplasm;Thylakoid space 89 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Proc Natl Acad Sci U S A 2003 Jan 7;100(1):98-103. Epub 2002 Dec 23. Science. 2004 Mar 19;303(5665):1831-8. Epub 2004 Feb 5. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Photosynth Res. 2005 Jun;84(1-3):153-9. Nature. 2005 Dec 15;438(7070):1040-4. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8567-72. doi: J Biol Chem. 2010 Aug 20;285(34):26255-62. doi: 10.1074/jbc.M110.127589. Epub J Biol Chem. 2011 May 6;286(18):15964-72. doi: 10.1074/jbc.M110.215970. Nature. 2011 May 5;473(7345):55-60. doi: 10.1038/nature09913. Epub 2011 Apr 17. Acta Crystallogr D Biol Crystallogr. 2012 Apr;68(Pt 4):352-67. doi: Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9721-6. doi: Science. 2013 Apr 26;340(6131):491-5. doi: 10.1126/science.1234273. Epub 2013 Feb Nature. 2014 Jul 9. doi: 10.1038/nature13453. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Photosystem II reaction center protein K precursor (PSII-K) Thermosynechococcus elongatus (strain BP-1) Q9F1K9 3.70 XRAY Interactions among CP47, CP43, D1, D2, and the three extrinsic proteins 33 kDa, 12 kDa, and cyt c550 in the luminal region. Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):98-103. cyt 550 (chains V, 0) are marked as Side2 in PDBTM therefore Side1=Inside 3.50 XRAY Single copies of each of the three extrinsic proteins, PsbO, PsbU, and PsbV, are located on the lumenal surface Science. 2004 Mar 19;303(5665):1831-8. Chain V is marked as Side2 in PDBTM, therefore Side1=Inside 3.00 XRAY according to fig 1 in 16355230 3.70 XRAY by similarity 4.00 XRAY by similarity 2.90 XRAY According to 19219048/Fig1 2.90 XRAY According to 19219048/Fig1 3.60 XRAY by similarity 3.20 XRAY by similarity 3.20 XRAY by similarity 6.56 XRAY by similarity 5.70 XRAY by similarity 5.90 XRAY by similarity 5.00 XRAY According to 25043005/Fig2 5.5 XRAY According to 21499260/Fig1 4.90 XRAY by similarity 4.60 XRAY by similarity 4.50 XRAY by similarity 5.2 XRAY by similarity MIDALVLVAK LPEAYAIFDP LVDVLPVIPV LFLALAFVWQ AAVGFR Bacterial thylakoid membrane;Cytoplasm;Thylakoid space 80 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Proc Natl Acad Sci U S A 2003 Jan 7;100(1):98-103. Epub 2002 Dec 23. Science. 2004 Mar 19;303(5665):1831-8. Epub 2004 Feb 5. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Nature. 2005 Dec 15;438(7070):1040-4. Nat Struct Mol Biol. 2009 Mar;16(3):334-42. doi: 10.1038/nsmb.1559. Epub 2009 Feb Proc Natl Acad Sci U S A. 2009 May 26;106(21):8567-72. doi: J Biol Chem. 2010 Aug 20;285(34):26255-62. doi: 10.1074/jbc.M110.127589. Epub J Biol Chem. 2011 May 6;286(18):15964-72. doi: 10.1074/jbc.M110.215970. Nature. 2011 May 5;473(7345):55-60. doi: 10.1038/nature09913. Epub 2011 Apr 17. Acta Crystallogr D Biol Crystallogr. 2012 Apr;68(Pt 4):352-67. doi: Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9721-6. doi: Science. 2013 Apr 26;340(6131):491-5. doi: 10.1126/science.1234273. Epub 2013 Feb Nature. 2014 Jul 9. doi: 10.1038/nature13453. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Sarcolipin Homo sapiens O00631 Q6ICV3 N/A NMR Residues 1 through 8, which constitute the small cytoplasmic domain, are mainly disordered. Biochemistry 2002 Jan 15;41(2):475-82. MGINTRELFL NFTIVLITVI LMWLLVRSYQ Y Sarcoplasmic reticulum membrane;Cytoplasm;Cysternal space 89 Structure PDBTM Structure PDBTM Structure PDBTM Biochemistry 2002 Jan 15;41(2):475-82. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit (Formate dehydrogenase-N beta subunit) (FDH-N beta subunit) (Anaerobic formate dehydrogenase iron-sulfur subunit) Escherichia coli P0AAJ3 P24184 P77166 1.60 XRAY >>The crystal structure indicates that a and b subunits of Fdh-N are on the periplasmic side of the membrane (Fig. 2C).<< Science 2002 Mar 8;295(5561):1863-8. 2.80 XRAY >>The crystal structure indicates that a and b subunits of Fdh-N are on the periplasmic side of the membrane (Fig. 2C).<< Science 2002 Mar 8;295(5561):1863-8. MAMETQDIIK RSATNSITPP SQVRDYKAEV AKLIDVSTCI GCKACQVACS EWNDIRDEVG HCVGVYDNPA DLSAKSWTVM RFSETEQNGK LEWLIRKDGC MHCEDPGCLK ACPSAGAIIQ YANGIVDFQS ENCIGCGYCI AGCPFNIPRL NKEDNRVYKC TLCVDRVSVG QEPACVKTCP TGAIHFGTKK EMLELAEQRV AKLKARGYEH AGVYNPEGVG GTHVMYVLHH ADQPELYHGL PKDPKIDTSV SLWKGALKPL AAAGFIATFA GLIFHYIGIG PNKEVDDDEE DHHE Bacterial inner membrane;Cytoplasm;Periplasmic space 95 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Science 2002 Mar 8;295(5561):1863-8. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Light-harvesting protein B-800/850, beta chain (Antenna pigment protein, beta chain) Rhodoblastus acidophilus P26790 2.5 XRAY >>alpha Trp45 the periplasmic key residue is also involved in B850 Bchl a coordination.<< J Mol Biol 1997 May 2;268(2):412-23. Trp45 is Side1 in PDBTM therefore Side1=Outside 2.00 XRAY >>The cytoplasmic surface (N terminus) is at the bottom of (c) and (d) where glucoside head groups of the first carotenoid (RG1) are located while at the periplasmic surface (C terminus, top ((a) and (d)) are located the glucosides of the second carotenoid (RG2).<< J Mol Biol 2003 Mar 7;326(5):1523-38. N-term: Side2 in PDBTM and C-term: Side1 in PDBTM. 2.45 XRAY >>The periplasmic surfaces in (a) and (b) are marked P: this surface is also the C-terminal surface of the peptides<< J Mol Biol. 2006 Apr 14;357(5):1605-18. This is Side1 in PDBTM. Therefore Side1=Outside. ATLTAEQSEE LHKYVIDGTR VFLGLALVAH FLAFSATPWL H Bacterial inner membrane;Cytoplasm;Periplasmic space 98 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure 1996 Apr 15;4(4):449-62. Curr Opin Struct Biol 1995 Dec;5(6):794-7. J Mol Biol 1997 May 2;268(2):412-23. J Mol Biol 2003 Mar 7;326(5):1523-38. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Mol Biol. 2006 Apr 14;357(5):1605-18. Epub 2006 Feb 2. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Light-harvesting protein B-800/850, alpha chain (Antenna pigment protein, alpha chain) Phaeospirillum molischianum P97253 2.4 XRAY >>both a- and 0-apoproteins should be oriented with their N-termini toward the cytoplasm.<< Protein Sci 1995 Sep;4(9):1670-82. SNPKDDYKIW LVINPSTWLP VIWIVATVVA IAVHAAVLAA PGFNWIALGA AKSAAK Bacterial inner membrane;Cytoplasm;Periplasmic space 100 Structure PDBTM Structure PDBTM Structure PDBTM Protein Sci 1995 Sep;4(9):1670-82. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Light-harvesting protein B-800/850, beta 1 chain (Antenna pigment protein, beta 1 chain) Phaeospirillum molischianum P95673 2.4 XRAY >>both a- and 0-apoproteins should be oriented with their N-termini toward the cytoplasm.<< Protein Sci 1995 Sep;4(9):1670-82. AERSLSGLTE EEAIAVHDQF KTTFSAFIIL AAVAHVLVWV WKPWF Bacterial inner membrane;Cytoplasm;Periplasmic space 99 Structure PDBTM Structure PDBTM Structure PDBTM Protein Sci 1995 Sep;4(9):1670-82. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Aa3-type cytochrome c oxidase subunit IV Rhodobacter sphaeroides Q8KRK5 2.30 XRAY by similarity 3.00 XRAY by similarity MAETNKGTGP MADHSHPAHG HVAGSMDITQ QEKTFAGFVR MVTWAAVVIV AALIFLALAN A Bacterial inner membrane;Cytoplasm;Periplasmic space 94 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM J Mol Biol 2002 Aug 9;321(2):329-39. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cardiac phospholamban (PLB) Oryctolagus cuniculus P61015 P20006 N/A NMR >>The overall structure of phospholamban is N/A MODEL by similarity N/A NMR by similarity N/A NMR According to 21576492/Fig4 N/A NMR by similarity N/A NMR by similarity MEKVQYLTRS AIRRASTIEM PQQARQNLQN LFINFCLILI CLLLICIIVM LL Plasma membrane;Cytoplasm;Extracellular 89 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Biophys J 2003 Oct;85(4):2589-98. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. Biochemistry. 2005 Mar 22;44(11):4302-11. J Biomol NMR. 2009 Aug;44(4):195-205. doi: 10.1007/s10858-009-9328-9. Epub 2009 Proc Natl Acad Sci U S A. 2011 May 31;108(22):9101-6. doi: Biochemistry. 2013 Sep 24;52(38):6684-94. doi: 10.1021/bi400517b. Epub 2013 Sep Structure. 2013 Dec 3;21(12):2119-30. doi: 10.1016/j.str.2013.09.008. Epub 2013 Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Light-harvesting protein B-870, alpha chain precursor (LH-1) (Antenna pigment protein, alpha chain) Rhodospirillum rubrum P02947 N/A MODEL by similarity N/A NMR by similarity MWRIWQLFDP RQALVGLATF LFVLALLIHF ILLSTERFNW LEGASTKPVQ TSMVMPSSDL AV Bacterial inner membrane;Cytoplasm;Periplasmic space 95 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Biochemistry. 2004 Feb 10;43(5):1276-82. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Mol Biol. 2005 Mar 25;347(2):465-77. Epub 2005 Jan 25. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Light-harvesting protein B-870, beta chain precursor (LH-1) (Antenna pigment protein, beta chain) Rhodospirillum rubrum P04125 P0C190 Q2RQ23 N/A MODEL by similarity N/A NMR by similarity MAEVKQESLS GITEGEAKEF HKIFTSSILV FFGVAAFAHL LVWIWRPWVP GPNGYSALET LTQTLTYLS Bacterial inner membrane;Cytoplasm;Periplasmic space 89 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Biochemistry. 2004 Feb 10;43(5):1276-82. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. J Mol Biol. 2005 Mar 25;347(2):465-77. Epub 2005 Jan 25. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome c oxidase subunit IV isoform 1, mitochondrial precursor (EC 1.9.3.1) (COX IV-1) (Cytochrome c oxidase polypeptide IV) Bos taurus P00423 Q3SZS0 Q5E991 2.8 XRAY >>Subunit Va, which is on the matrix side<< Science. 1996 May 24;272(5265):1136-44. Chain E is marked as Side2 in PDBTM 2.8 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 2.35 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 2.9 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.80 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.90 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.80 XRAY by similarity 2.20 XRAY by similarity 1.90 XRAY by similarity 2.10 XRAY by similarity 2.10 XRAY by similarity 2.60 XRAY by similarity 2.70 XRAY by similarity 2.3 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.95 XRAY by similarity 19.00 XRAY by similarity 2.50 XRAY by similarity 2.00 XRAY by similarity 2.10 XRAY by similarity 1.95 XRAY by similarity 2.20 XRAY by similarity 1.80 XRAY by similarity 1.80 XRAY by similarity 2.05 XRAY by similarity 3.00 XRAY by similarity 2.30 XRAY by similarity 1.90 XRAY by similarity MLATRVFSLI GRRAISTSVC VRAHGSVVKS EDYALPSYVD RRDYPLPDVA HVKNLSASQK ALKEKEKASW SSLSIDEKVE LYRLKFKESF AEMNRSTNEW KTVVGAAMFF IGFTALLLIW EKHYVYGPIP HTFEEEWVAK QTKRMLDMKV APIQGFSAKW DYDKNEWKK Mitochondrial inner membrane;Matrix;Inter membrane space 97 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Science 1995 Aug 25;269(5227):1069-74. Science 1996 May 24;272(5265):1136-44. Science 1998 Jun 12;280(5370):1723-9. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15304-9. Epub 2003 Dec 12. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. EMBO J. 2007 Mar 21;26(6):1713-25. Epub 2007 Mar 1. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7881-6. Epub 2007 Apr 30. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2165-9. doi: Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Mar 1;66(Pt 3):251-3. doi: Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7740-5. doi: Biochim Biophys Acta. 2011 Jul;1807(7):769-78. doi: 10.1016/j.bbabio.2010.12.016. Acta Crystallogr D Biol Crystallogr. 2011 Aug;67(Pt 8):742-4. doi: EMBO J. 2011 Sep 9;30(22):4652-64. doi: 10.1038/emboj.2011.324. Nat Methods. 2014 Jul;11(7):734-6. doi: 10.1038/nmeth.2962. Epub 2014 May 11. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome c oxidase polypeptide VIa-heart, mitochondrial precursor (EC 1.9.3.1) (COXVIAH) (Polypeptide VIb) Bos taurus P07471 Q3SZ61 2.8 XRAY >>Subunit Va, which is on the matrix side<< Science. 1996 May 24;272(5265):1136-44. Chain E is marked as Side2 in PDBTM 2.8 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 2.35 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 2.9 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.80 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.90 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.80 XRAY by similarity 2.20 XRAY by similarity 1.90 XRAY by similarity 2.10 XRAY by similarity 2.10 XRAY by similarity 2.60 XRAY by similarity 2.70 XRAY by similarity 2.3 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.95 XRAY by similarity 19.00 XRAY by similarity 2.50 XRAY by similarity 2.00 XRAY by similarity 2.10 XRAY by similarity 1.95 XRAY by similarity 2.20 XRAY by similarity 1.80 XRAY by similarity 1.80 XRAY by similarity 2.05 XRAY by similarity 3.00 XRAY by similarity 2.30 XRAY by similarity 1.90 XRAY by similarity MALPLKSLSR GLASAAKGDH GGTGARTWRF LTFGLALPSV ALCTLNSWLH SGHRERPAFI PYHHLRIRTK PFSWGDGNHT FFHNPRVNPL PTGYEKP Mitochondrial inner membrane;Matrix;Inter membrane space 96 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Science 1995 Aug 25;269(5227):1069-74. Science 1996 May 24;272(5265):1136-44. Science 1998 Jun 12;280(5370):1723-9. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15304-9. Epub 2003 Dec 12. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. EMBO J. 2007 Mar 21;26(6):1713-25. Epub 2007 Mar 1. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7881-6. Epub 2007 Apr 30. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2165-9. doi: Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Mar 1;66(Pt 3):251-3. doi: Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7740-5. doi: Biochim Biophys Acta. 2011 Jul;1807(7):769-78. doi: 10.1016/j.bbabio.2010.12.016. Acta Crystallogr D Biol Crystallogr. 2011 Aug;67(Pt 8):742-4. doi: EMBO J. 2011 Sep 9;30(22):4652-64. doi: 10.1038/emboj.2011.324. Nat Methods. 2014 Jul;11(7):734-6. doi: 10.1038/nmeth.2962. Epub 2014 May 11. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome c oxidase polypeptide VIc (EC 1.9.3.1) (STA) Bos taurus P04038 A0JNM4 2.8 XRAY >>Subunit Va, which is on the matrix side<< Science. 1996 May 24;272(5265):1136-44. Chain E is marked as Side2 in PDBTM 2.8 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 2.35 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 2.9 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.80 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.90 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.80 XRAY by similarity 2.20 XRAY by similarity 1.90 XRAY by similarity 2.10 XRAY by similarity 2.10 XRAY by similarity 2.60 XRAY by similarity 2.70 XRAY by similarity 2.3 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.95 XRAY by similarity 19.00 XRAY by similarity 2.50 XRAY by similarity 2.00 XRAY by similarity 2.10 XRAY by similarity 1.95 XRAY by similarity 2.20 XRAY by similarity 1.80 XRAY by similarity 1.80 XRAY by similarity 2.05 XRAY by similarity 3.00 XRAY by similarity 2.30 XRAY by similarity 1.90 XRAY by similarity STALAKPQMR GLLARRLRFH IVGAFMVSLG FATFYKFAVA EKRKKAYADF YRNYDSMKDF EEMRKAGIFQ SAK Mitochondrial inner membrane;Matrix;Inter membrane space 95 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Science 1995 Aug 25;269(5227):1069-74. Science 1996 May 24;272(5265):1136-44. Science 1998 Jun 12;280(5370):1723-9. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15304-9. Epub 2003 Dec 12. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. EMBO J. 2007 Mar 21;26(6):1713-25. Epub 2007 Mar 1. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7881-6. Epub 2007 Apr 30. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2165-9. doi: Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Mar 1;66(Pt 3):251-3. doi: Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7740-5. doi: Biochim Biophys Acta. 2011 Jul;1807(7):769-78. doi: 10.1016/j.bbabio.2010.12.016. Acta Crystallogr D Biol Crystallogr. 2011 Aug;67(Pt 8):742-4. doi: EMBO J. 2011 Sep 9;30(22):4652-64. doi: 10.1038/emboj.2011.324. Nat Methods. 2014 Jul;11(7):734-6. doi: 10.1038/nmeth.2962. Epub 2014 May 11. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome c oxidase polypeptide VIIa-heart, mitochondrial precursor (EC 1.9.3.1) (Cytochrome c oxidase subunit VIIa-H) (COX VIIa-M) (VIIIC) Bos taurus P07470 A4FUH9 2.8 XRAY >>Subunit Va, which is on the matrix side<< Science. 1996 May 24;272(5265):1136-44. Chain E is marked as Side2 in PDBTM 2.8 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 2.35 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 2.9 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.80 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.90 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.80 XRAY by similarity 2.20 XRAY by similarity 1.90 XRAY by similarity 2.10 XRAY by similarity 2.10 XRAY by similarity 2.60 XRAY by similarity 2.70 XRAY by similarity 2.3 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.95 XRAY by similarity 19.00 XRAY by similarity 2.50 XRAY by similarity 2.00 XRAY by similarity 2.10 XRAY by similarity 1.95 XRAY by similarity 2.20 XRAY by similarity 1.80 XRAY by similarity 1.80 XRAY by similarity 2.05 XRAY by similarity 3.00 XRAY by similarity 2.30 XRAY by similarity 1.90 XRAY by similarity MRALRVSQAL VRSFSSTARN RFENRVAEKQ KLFQEDNGLP VHLKGGATDN ILYRVTMTLC LGGTLYSLYC LGWASFPHKK Mitochondrial inner membrane;Matrix;Inter membrane space 96 Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Structure PDBTM Science 1995 Aug 25;269(5227):1069-74. Science 1996 May 24;272(5265):1136-44. Science 1998 Jun 12;280(5370):1723-9. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15304-9. Epub 2003 Dec 12. Bioinformatics. 2004 Nov 22;20(17):2964-72. Epub 2004 Jun 4. EMBO J. 2007 Mar 21;26(6):1713-25. Epub 2007 Mar 1. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7881-6. Epub 2007 Apr 30. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2165-9. doi: Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Mar 1;66(Pt 3):251-3. doi: Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7740-5. doi: Biochim Biophys Acta. 2011 Jul;1807(7):769-78. doi: 10.1016/j.bbabio.2010.12.016. Acta Crystallogr D Biol Crystallogr. 2011 Aug;67(Pt 8):742-4. doi: EMBO J. 2011 Sep 9;30(22):4652-64. doi: 10.1038/emboj.2011.324. Nat Methods. 2014 Jul;11(7):734-6. doi: 10.1038/nmeth.2962. Epub 2014 May 11. Copyrighted by the Institute of Enzymology, see http://topdb.enzim.hu/?m=terms. Distributed under the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) License Cytochrome c oxidase polypeptide VIIb, mitochondrial precursor (EC 1.9.3.1) (IHQ) Bos taurus P13183 Q3SZ39 2.8 XRAY >>Subunit Va, which is on the matrix side<< Science. 1996 May 24;272(5265):1136-44. Chain E is marked as Side2 in PDBTM 2.8 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 2.35 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 2.9 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.80 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.90 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.80 XRAY by similarity 2.20 XRAY by similarity 1.90 XRAY by similarity 2.10 XRAY by similarity 2.10 XRAY by similarity 2.60 XRAY by similarity 2.70 XRAY by similarity 2.3 XRAY Chain E (subunit Va) is marked as Side2 in PDBTM, and it is on matrix side. 1.95 XRAY by similarity 19.00 XRAY by similarity 2.50 XRAY by similarity 2.00 XRAY by similarity 2.10 XRAY by similarity 1.95 XRAY by similarity 2.20 XRAY by similarity 1.80 XRAY by similarity 1.80 XRAY by similarity 2.05 XRAY by similarity 3.00 XRAY by similarity 2.30 XRAY by similarity 1.90 XRAY